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Cirrhosis
is obstruction and fibrosis of the portal circulation which can lead to all of these no matter the
cause:
decreased albumin always
this leads to edema and ascites
so we give Spironolactone which inhibits the aldosterone
we have to tap the ascites and check the albumin level
...
1 (here albumin in
the Ascites is low) then it’s related to portal hypertension => Transudative
if SAAG <1
...
Fatty liver (steatosis)
is the result of short term alcohol ingestion
2
...
Alcoholic fibrosis/cirrhosis
...


**Patients with severe liver disease can develop systemic hypoperfusion and subsequent
renal failure, sometimes referred to as hepatorenal syndrome
...
The
absence of protein or blood on urinalysis makes intrinsic renal disease less likely**
**Patients with cirrhosis should undergo screening endoscopy to exclude varices, indicate the
risk of variceal hemorrhage, and determine strategies (eg, nonselective beta blockers) for
primary prevention of variceal hemorrhage
...
Cirrhosis due to alcohol or hemochromatosis is
most commonly associated with hypogonadism
...
The liver is also responsible for making
serum binding proteins for triiodothyronine (T3} and thyroxine (T4} such as thyroxine-binding
globulin, transthyretin, albumin, and lipoproteins
...
However, free

T3 or T4 concentration is usually unchanged as nearly all T3 and T4 is bound to the serum
binding proteins**



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