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Title: DNA and RNA notes
Description: DNA and RNA study notes used for first year bachelor of Biomedical science at Queensland University of Technology. Basic foundation for anyone studying or wanting to study biology or medicine at university.
Description: DNA and RNA study notes used for first year bachelor of Biomedical science at Queensland University of Technology. Basic foundation for anyone studying or wanting to study biology or medicine at university.
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182 Lecture 10 DNA & RNA
NUCLEIC ACID
Gene coding à codon = 3 nucleotides
DNA
- Directs RNA synthesis
- Genetic material inherited from parents
RNA
- Phosphate + sugar backbone with Nitrogenous base
o Ribose sugar = 5 carbon
§ RNA =OH
§ DNA = H (deoxy = no oxygen)
§ Connects 5’-3’
§ Represented with R on structural drawings
o Phosphoric acid
§ Can lose/gain H+ depending on the pH (pKa)
§ DRAWING
PYRIMIDINES
- Uracil
- Cytosine
- Thymine
PURINES
- Adenine
- Guanine
NUCLEOSIDES
A base joined to the anomeric carbon of ribose sugar
NUCLEOTIDE
Nucleoside + phosphate (joined to 5’ and attaches to 3’ of the next)
DNA & RNA:
- Informational = Genomic DNA & messenger RNA
- Structural = Ribosomal RNA & Transfer RNA
o Genomic DNA
§ 2 separate nucleic acid polymer strands (antiparallel)
§ Many hydrogen bonds between the bases
§ 10 base pairs between each helix loop
BASES
Bases
Common name
Adenine
Adenosine triphosphate
Cytosine
Cytodine Triphosphate
Guanine
Guanosine Triphosphate
Thymine
Thymidine triphosphate
Uracil
Uridine triphosphate
Title: DNA and RNA notes
Description: DNA and RNA study notes used for first year bachelor of Biomedical science at Queensland University of Technology. Basic foundation for anyone studying or wanting to study biology or medicine at university.
Description: DNA and RNA study notes used for first year bachelor of Biomedical science at Queensland University of Technology. Basic foundation for anyone studying or wanting to study biology or medicine at university.