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Title: Practice papers
Description: Some questions you would love to solve .. Check Out ..

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PHARMACOPHORE SOLUTIONS-JAIPUR
Q
...

[R] Can be hydrolysed to an alkaloid
...

Choose the correct option
...
B
Q
...

[Q] It is obtained from Panax ginseng and Panax quinquefolium
...

[S] It contains derivatives of protopanaxadiol
...
D (MINOR TEST)
Q
...
A (MINOR TEST)
Q
...
B (MINOR TEST)
Q
...
Find a WRONG combination
...
D (MINOR TEST-50% SIMILAR –B & A OPTION ARE DIFFERENT FROM OUR QUESTION)
Q
...
A (MAJOR PAPER)
Q
...

Choose an option showing a WRONG combination
...
C
Q
...
B (MINOR TEST )

Q
...
D (MIN OR TEST - AS IN T HAT Q
...
10

Khellin is an active constituent of which one of the following plants?
(A) Prunus serona

(B)

(C) Ammi visnaga

(D) Vanilla plamfolia

ANS
...
GPATINDIA
...
l1

Goldbeater's skin test is used to detect the presence of which one of the following classes of compounds?
(A) Tannins

(B)

Steroids

(C)

Glycerides

(D) Resins

ANS
...
12

Which one of the following compounds is useful for the stimulation of cell division and release of lateral bud
dormancy?
(A)

Zeatin

(B) 2, 4-Dichlorophenoxyacetic acid

(C)

Indoleacetic acid

(D) Picloram

ANS
...
13

Phenylethylisoquinoline is the precursor of which of the following alkaloids?
(A)

Colchicine

(B)

Papaverine

(C) Emetine

(D) Cephaline

ANS
...
14

A powdered drug has the following microscopic characters:
Anther cells, arenchyma, pollen grains, phloem fibers, volatile oil cells and stone cells
...
B
Q
...
C
Q
...

Hydrolysable and condensed tannins are differentiated by match stick test
...


(A)

Both (a) and (r) are true, and (r) is a correct reason for (a)

(B)

Both (a) and (r) are true, but (r) is NOT the correct reason for (a)

(C)

(a) is true but (r) is NOT the correct reason for (a)

(D)

Both (a) and (r) are false

ANS
...
ARE VERY IMP
...
IN EVERY TEST U GET
AROUND 3-5 QUE)

Q
...

Reason (r)
(A)
(B)

: The oil contains ricinoleic acid having a hydroxyl group at C-12 position which is responsible
for its solubility in alcohol and its purgative action
...
C (SEMI MAJOR TEST)
Q
...

[P] Geranyl pyrophosphate contains two isoprene units
[Q] Monoterpenes have 15 carbon atoms
[R] The two isoprene units condense in head to tail fashion to give Monoterpenes
[S] Isoprene unit has molecular formula of C5 Hs
...
Q is false, R is true, S is false

(B)

P is false
...
Q is true, R is false, S is true

(D) P is

true
...
D

WWW
...
COM

PHARMACOPHORE SOLUTIONS-JAIPUR
Q
...
e
...

[P] Drug type cannabis is rich in (-) A9-£rarcs-tetrahydrocannabinol
...
S is true
false, Q is false, R is true, S is false

ANS
...
20 Each of the following options lists a phytoconstituent, its phytochemical grouping, pharmacological activity
and corresponding semi synthetic analogue
...

(A)
(B)
(C)
(D)

Podophyllotoxin, lignan, anticancer, etoposide
Sennoside, anthraquinone, laxative, sinigrin
Atropine, alkaloid, anticholinergic, homatropine
THC, terpenophenolic, psychoactive, nabilone

ANS
...
21 Inhibition/induction of which of the following Cytochrome P450 enzyme system is most likely to be involved in
important drug-drug interactions?
(A) CYP3A4

(B) CYP2D6

(C) CYP2C9

(D) CYP1A2

An s
...
22 Which of the following mechanisms is NOT related to platelet aggregation inhibitory action?
(A)
(B)
(C)
(D)

ADP receptor antagonism
Glycoprotein Ilb/IIIa receptor antagonism
Phosphodiesterase inhibition
Prostacyclin inhibition

ANS
...
23

Choose the correct statement about the given four diseases?
[P] Cardiomyopathy
[R] Myasthenia gravis

[Q] Rheumatoid arthritis
[S] Ulcerative colitis

(A)
(B)

Q & S are autoimmune disorders
P & Q are autoimmune disorders

(C)

P & R are not autoimmune disorders

(D)

R & S are not autoimmune disorders

ANS
...
24

Which

of

the

(A) Oxytocin

following

species

is

(B) Vasopressin

being

inactivated
(C) Incretins

by

the

enzyme

Dipeptidyl

peptidase-4?

(D) Glucagon

ANS
...
It is responsible for the degradation of
incretins such as GLP-1
Q
...
This drugdrug interaction causes which of the following actions?
Severe hypotension

(A)

Respiratory failure

(B)

(C)

Prolongation of QT interval

(D) Myocardial ischemia

ANS
...
26 Which of the following drugs does NOT induce mydriasis?
(A) Atropine

(B) Ephedrine

(C)

Phentolamine '(D) Cocaine

ANS C (MINOR TEST)
Q
...
A

WWW
...
COM

[PHARMACOPHORE SOLUTIONS-JAIPUR]

Q
...
B
Q
...
Choose the correct statement about them
...
A
Q
...
B (MINOR TEST)
Q
...
B
Q
...
D (MAJOR TEST-1)
Q
...
C (MAJOR TEST -1)

Q
...
A (MINOR TEST- AS IN THAT Q
...
35 What is chemotaxis?
(A)

Toxicity of chemicals

(B)

Taxonomy of chemicals

(C)

Inhibition of Inflammation

(D)

Movement of leucocytes in inflammation

ANS
...
36

Which one of the followings is NOT an example of G-protein coupled receptor?
(A) Muscarinic cholinergic receptor
(C) Nicotinic cholinergic receptor

(B) Alpha adrenoceptor
(D) Beta adrenoceptor

ANS
...
37

Which of the followings used in the treatment of rheumatoid arthritis is NOT a biologic response modifier?
(A) Anakinra

(B) Leflunomide

(C) Etanercept

ANS
...
WE ASKED- ABOUT TNF)

WWW
...
COM

V"(6) Infliximab

PHARMACOPHORE SOLUTIONS-JAIPUR
Q
...
B (MINOR TEST)
Q
...
B

Q
...
B
Q
...
B (MAJOR TEST)
Q
...
C (MINOR TEST- AS WE ASKED-5α-reductase INHIBITOR IS?)
Q
...
C (MINOR TEST)

Q
...
D (MINOR TEST)
Q
...

(A) Parkinson's disease and Alzheimer's disease
(B)

Schizophrenia and Mania

(C)

Alzheimer's disease and Schizophrenia

(D)

Parkinson's disease and Autism

ANS
...
46 A 64 year old woman with a history of Type II diabetes is diagnosed with heart failure
...
B (MINOR TEST)
Q
...
The action is caused
due to which of the following mechanisms?
(A)
(B)
(C)
(D)

Mifepristone
Mifepristone
Mifepristone
Mifepristone

is
is
is
is

an
an
an
an

antiestrogen while gemeprost is a prostaglandin E receptor agonist
...

antiandrogen while gemeprost is a prostaglandin E receptor agonist
...
B
Q
...
Which one of the followings is a beta lactamase inhibitor?
Embonic acid

(A) Penicillanic acid

(B)

(C) Cephalosporanic acid

(C) Clavulanic acid

Ans
...
GPATINDIA
...
49

All of the followings are indications for use of ACE inhibitors EXCEPT for one
...


(A) Hypertension

(B) Myocardial infarction

(C) Left ventricular dysfunction

(D) Pheochromocytoma

ANS
...
50

Neural tube defects may occur by which one of the following anti-seizure drugs?

(A) Ethosuximide

(B) Vigabatnn

(C) Valproic acid

(D) Primidone

ANS
...
51

Which water is used for hand washing in a change room of pharmaceutical manufacturing plant?

(A) Potable water

(B) Purified water

(C ) Disinfectant water

(D)

Soap water

ANS
...
52 Which one of the following drying methods is commonly used in Pharma industry for drying of soft shell
capsules?
Fluid bed drying

(A) Truck drying
...
C
Q
...
D (Ref
...
ub
...
nl/FILES/faculties/science/1990/h
...
frijlink/c1
...
54
...
In which case the sink
conditions are said to be maintained?
(A) C < 20% of Cs (B) C > 20% of Cs

(C) C < 10% of Cs (D) C > 10% of Cs

ANS
...
55 Which condition does not apply as per Indian law while conducting single dose bioavailability study of an
immediate release product?
(A)

Sampling period should be at least three t1/2 el

(B)

Sampling should represent pre-exposure, peak exposure and post-exposure phases

(C)

There should be at least four sampling points during elimination phase

(D)

Sampling should be continued till measured AUC is at least equal to 80% of AUC

ANS
...
56 Upon standing sometimes gel system shrinks a bit and little liquid is pressed out
...
B (A process by which a fluid exudate forms on the surface of a hydrocolloid gel, even when the gel is in
water or in a S humid atmosphere
...

Read more: http://www
...
com/topic/syneresis
Q
...
B
Q
...

[Q] IgG provides immunity to new born babies while IgM is the first generated antibody
...
C (MAJOR TEST)
Q
...
A and B (MAJOR TEST) also known as Geobacillus stearothermophilus (Spores)

WWW
...
COM

PHARMACOPHORE SOLUTIONS-JAIPUR
Q
...

(A) Both P and Q are true

(B) P is true, Q is false

(C) Q is true
...
A

Q
...
7 nm

(B) 275
...
5 nm

(D) 240
...
A
Q
...
typhi
Rideal-Walker test uses organic matter in media
The organism in Chick Martin test is S
...
C (MINOR TEST- AS WE ASKED ABOUT RIDEAL WALKER TEST)
Q
...
D

Q
...
D
Q
...
B (MINOR TEST)

Q
...
(B) 50

(C) 100

(D) 1000

ANS
...
67

Which of the following Schedules include shelf life of drugs?

(A) Schedule F

(B) Schedule M

(C) Schedule G

(D) Schedule P

ANS
...
68

Which of the following pumps is used in handling of corrosive liquids?

(A) Turbine pump
(C) Air binding pump

(B) Volute pump
(D) Peristaltic pump

ANS
...
69

By addition of which of the followings the shells of soft gelatin capsules may be made elastic?

(A) Polyethylene glycol
(C) Propylene glycol

(B) Sorbitol
(D) Dibutyl phthalate

ANS
...
GPATINDIA
...
70

Convert 90% v/v alcohol to Proof strength
...


(A) 57
...
77° over proof

(C) 47
...
41° under proof

ANS
...
71

Department of Transport Test (DOT) is performed for which of the followings?
(A) Strip packing
(C) Injection packing

(B) Aerosols
(D) Glass containers

ANS
...
72

What is the Heat of vaporization of water at 100°C?

(A) 2790 cal/mole

(B) 7290 cal / mole

(C) 7920 cal/mole

(D) 9720 cal / mole

ANS
...
73

Determine the correctness or otherwise of the following Assertion [a] and the Reason [r]:

Assertion [a]: For a pharmaceutical powder true density is greater than the granule density
...

(A)

[a] is true but [r] is false

(B)

Both [a] and [r] are false

(C)

Both la] and [r] are true and [r] is the correct reason for [a]

(D)

Both [a] and [r] are true but [r] is NOT the correct reason for [a]

ANS
...
74

Determine the correctness or otherwise of the following statements:

[P] Rheopexy is the phenomenon when a sol forms gel more readily when sheared gently
...

[R] Rheopexy is a phenomenon when a sol forms gel when the material is kept at rest
...
B
Q
...

The process of collecting plasma and returning the red blood cells concentrate to the donor
The process of collecting red blood cells concentrate and returning the plasma to the donor

(C)

The process of separating white blood cells from blood

(D)

The process of generating artificial blood plasma expanders

ANS
...
76 Molecules in the smectic liquid crystals are characterized by which one of the followings?
(A)

Mobility in three directions and rotation in one axis

(B)

Mobility in two directions and rotation in one axis

(C)

Mobility in two directions and no rotation

(D)

Mobility in three directions and no rotation

ANS
...
77

Choose the correct sequence of Moisture Vapor Transmission Rate in packaging materials?

(A)

Paper > Aluminium foil > PVC > PVdC

(B)

Aluminium foil > PVC > PVdC > Paper

(C)

Aluminium foil > PVdC > PVC > Paper

(D)

Paper > PVC > PVdC > Aluminium foil

ANS
...
78 How many mL of 50% (w/v) dextrose solution and how many mL of 5% (w/v) dextrose solution are required
to prepare 4500 mL of a 10% (w/v) solution?
(A)
(B)
(C)
(D)

500 mL of 50% and 4000 mL of 5%
1000 mL of 50% and 3500 mL of 5%
4000 mL of 50% and 500 mL of 5%
1500 mL of 50% and 3000 mL of 5%

ANS
...
GPATINDIA
...
79
A drug is administered to a 65 Kg patient as 500 mg tablets every 4 hours
...
85
...
05mcg/ml

(B) 4
...
53 mcg/ml

(D) 3
...
D
Q
...
A
Q
...

Statement [Y]: The relative coagulating power is given by:
[P] Al+++ > Ba++

[Q] Li - > F-

[R] NH+ > Na +

Choose the correct statement:
(A)
(B)
(C)
(D)

Statement
Statement
Statement
Statement

X
X
X
X

is true but P, Q and R are false in Statement Y
is false and P, Q and R are false in Statement Y
is true and Q and R are false in Statement Y
is false and P is false in Statement

ANS
...
82

The first stage of wetting on addition of a granulating agent to the powders is characterized by which one of
the followings?
(A) Capillary state

(B) Pendular state

(C)Funicular state

(D) Droplet state

ANS
...
83

Larger values of Ky in the Heckel Plot indicate formation of what quality of tablets?
(A) Harder tablets
(C) Fluffy tablets

(B) Softer tablets
(D) Brittle tablets

ANS
...
84

The degree of flocculation of a suspension is 1
...
75
...
0

(B) 1
...
75

(D) 0
...
D (Physical Pharmacy by Dr
...
B
...
112)
Q
...
6/hr to be
degraded from initial concentration of 100 mg/ml to 10 mg/ml?
(A) 2 hr

(B) 4hr

(C) 9 hr

(D)

0
...
D (APRROX ANSWER-0
...
86

What will be the dose required maintaining therapeutic concentration of 20 microgram/ml
for 24 hr of a drug exhibiting total clearance of 2 L/hr?
(A)

96 mg

(B) 480 mg

(C)

960 mg

(D) 48 mg

ANS
...
86 Which website first provides answer key of GPAT-11?
(A)

Gpatindia
...
C
Q
...
C
Q
...
B (MINOR TEST)

WWW
...
COM

PHARMACOPHORE SOLUTIONS-JAIPUR
Q
...
A
Q
...
A
Q
...
C (MINOR TEST)
Q
...
C
Which of the followings is NOT a reciprocating pump?

Q
...
C
Q
...
D
Q
...

Statement [Q] : Hard gelatin capsule shells contain 6-10 % moisture
...
B (MINOR TEST – AS WE ASKED ABOUT MOISTURE CONTENT OF SOFT GELATIN
CAPSULE)
Q
...
C (+/- 4%)
Q
...

The drug belongs to which class according to the BCS classification?
(A) Class I

(B) Class II

(C) Class III

(D) Class IV

ANS
...
98

Which statement is NOT true for steam distillation?
(A)
(B)

It is also called differential distillation
It can be used for separation of immiscible liquids

(C)

It can be applied for volatile substances

(D)

It can be used for separation of miscible liquids

ANS
...
99

The area of clear opening of any two successive sieves according to Tyler standard is in the
ratio of,
(A) 1 : 4

(B) 1 : 6

(C) 1 : √2

(D) 1 : √3

ANS
...
GPATINDIA
...
100 What is Primogel?
(A)

Substituted HPMC for direct compression

(B)

Modified microcrystalline cellulose for direct compression

(C)

Hydro gelling polymer for gel formation

(D)

Modified starch for disintegration

ANS
...
“Pharmacophore Solutions”
have launched a target NIPER programme for those who are really serious about their admission

in NIPERs
...
These papers were
prepared by NIPERites under the guidance of their faculties
...
25 mark will be deducted for every
wrong answer

Note: Whenever you go through online examination you should have a note book (Rough blank
papers) with your pen
...

Q
...
Choose the correct statement out of the followings?
(A)
(B)
(C)
(D)

Stannous fluoride is an anticaries agent while calcium pyrophosphate is a dentifrice
Stannous fluoride is a dentifrice while calcium pyrophosphate is a desensitizing agent
Stannous fluoride is a desensitizing agent while calcium pyrophosphate is an anticaries
agent
Both are dentifrices while calcium pyrophosphate is additionally a desensitizing agent

ANS
...
102 Hydrogen peroxide solution (20 volumes) is used topically as a mild antiseptic
...

[P] Astringent action
[R] Oxidizing action

[Q] Nascent hydrogen releasing action
[S] Mechanical cleansing action

Choose the correct statements for the use of hydrogen peroxide as cleaning agent for wounds?
(A)P&R

(B)

P&Q

(C)

R&Q

(D) R & S

ANS
...
103 Magnesium trisilicate is considered to be a better antacid than aluminium hydroxide due to its
following additional properties:
[P] It has a fixed chemical composition
[Q] It forms colloidal silicone dioxide
[R] Magnesium ions overcome constipation
[S] Magnesium ions cause higher inhibition of pepsin than aluminium ions
Choose the correct combination of statements?
(A) Q & S

(B)

R&S

(C) P & Q

(D) Q & R

ANS
...
104 Boric acid is a weak acid (pKa 9
...
This titration becomes possible on
addition of glycerol due to one of the following reactions
...
C

WWW
...
COM

PHARMACOPHORE SOLUTIONS-JAIPUR

Q
...
e
...
Which one of the following compounds meet the
above two requirements most closely?
(A) Ferric chloride
(C) Ferric ammonium citrate

(B) Ferric ammonium sulphate
(D) Ferrous thioglycollate

ANS
...
106 Iodine-131 as sodium iodide solution is used as a radiopharmaceutical for diagnostic and
therapeutic purposes
...
A (MINOR TEST)
Q
...
C (MINOR TEST-ONLY C & D OPTION ARE CHANGE FROM OUR QUESTION)
Q
...
If an electron withdrawing group is
attached to one of the carbons bearing the double bond, what will happen to the mechanism
of the addition reaction?
(A) It remains electrophilic

(B) It becomes free radical addition

(C) It becomes pericyclic reaction (D) It becomes nucleophilic
ANS- D
Q
...
Enhancement in the rate of
such reactions is due to which one of the following effects?
(A)

Solvation of the anion by the solvent leaving the cation unaffected

(B)

Solvation of both of the ionic species

(C)

Desolvation of the cation and solvation of the anion

(D)

Solvation of the cation by the solvent leaving the anion unaffected

ANS
...
110 Five-membered heteroaromatic compounds show a much higher rate of electrophilic aromatic
substitution reactions than the six-membered ones
...
A
Q
...
This is due to which of the following facts?
(A) Lone pair of electrons on N in pyrrole is localized
(B)
(C)
(D)

Lone pair of electrons on N in pyridine is localized
Nitrogen of pyrrole has one hydrogen atom attached to it while pyridine does not have
any
Pyridine has three double bonds while pyrrole has only two

ANS
...
112 Diels-Alder reaction can be carried out in which of the following heterocyclic compounds most
readily?
(A) Pyrrole

(B) Thiophene

(C) Furan

ANS
...
GPATINDIA
...
113 In nucleophilic aliphatic substitution reactions arrange the following leaving groups in
decreasing order of their leaving capacity?
[P] Brosyl[Q] Hydroxyl

[R] Chloro

(A) S > R > P > Q

(B) P > S > R > Q

(C) R > Q > S > P

[S] Mesyl

(D) R > S > Q > P

ANS
...
114 Determine the correctness or otherwise of the following Assertion [a] and the Reason [r]:
Assertion (a) : Quaternary ammonium phase transfer catalysts can enhance the rate of
nucleophilic aliphatic substitutionreactions in biphasic systems with water soluble
nucleophiles
...

(A)

Both (a) and (r) are true but (r) is not the correct reason for (a)

(B)

Both (a) and (r) are true and (r) is the correct reason for (a)

(C)

(a) is true (r) is false

(D)

Both (a) and (r) are false

ANS
...
115 Which one of the given compounds can be used as primary standard for standardization of
perchloric acid solution in non-aqueous titrations?
(A) Potassium hydrogen phthalate

(B) Sodium bicarbonate

(C) Potassium dihydrogen phosphate

(D) Sodium methoxide

ANS
...
116 In context of complexometry (complexometric titrations), the two terms labile and inert
complexes, are used frequently
...
C
Q
...
Choose the correct
statement about them?
(A)
(B)
(C)
(D)

Indicator-metal ion complex should have higher stability than EDTA-Metal ion complex
Indicator-metal ion complex should have lower stability than EDTA-Metal ion complex
Indicator-metal ion complex should have equal stability as EDTA-Metal ion complex
Stability of the indicator-metal ion complex is not an important criterion in
complexometric titrations

ANS
...
118 In colorimetric estimation of a drug, the following sequence of reactions is carried out:
treatment of the aqueous solution of the drug with sodium nitrite solution in acidic medium
followed by addition of sulphamic acid and then treatment with N-(l-naphthyl) ethylenediamine in slightly basic medium to obtain a pink colour; which is measured at a fixed
wavelength to correlate the quantity of the drug with the optical density
...
D
Q
...
A (SEMI MAJOR PAPER 2)

WWW
...
COM

PHARMACOPHORE SOLUTIONS-JAIPUR
Q
...
337
V and - 0
...
If the half cells of both of these metals are connected externally
to each other through an external circuit and a salt bridge, which one of the following
processes will take place?
(A)

(C)

Zinc metal electrode will start dissolving in solution while copper ions will start
depositing on the copper electrode
...
A
Q
...
DME has a number of advantages
...
It means which one of the followings?
(A)

Hydrogen ions get easily reduced on the DME

(B)

Hydrogen gas gets easily reduced on the DME

(C)

Hydrogen ions require high potential to be reduced at DME

(D)

Water is difficult to get oxidized at DME

ANS
...
122 Following are the desirable properties of the liquid phase used in GLC EXCEPT for one of the
followings
...

(A)

It should be inert to the analytes

(B)

It should have high viscosity at operating temperature

(C)
(D)

It should have low vapour pressure at the operating temperature
It should have a high resolving power

ANS
...
123 In HPLC analysis what type of column would you prefer?
(A)

A column with high HETP and high number of plates

(B)

A column with low HETP and low number of plates

(C)

A column with high HETP and low number of plates

(D)

A column with low HETP and high number of plates

ANS
...
124 To synthesize sulphonyl urea antidiabetic, which of the following reactions can be used?
(A)

Reacting a suitably substituted sulphonyl chloride with a desired urea derivative under
basic conditions

(B)

Reacting a suitably substituted sulphonamide with a desired isocyanate derivative

(C)

Reacting a suitably substituted sulphonic acid with a desired isocyanate derivative

(D)

Reacting a suitably substituted sulphoxide with a desired urea derivative

ANS
...
125 In an optically active organic compound a chiral carbon has the following attached groups:

[S] ─C≡C

[R] -CH = CH2

Using 'Sequence Rules' choose the correct order of
priority of the groups?
(A) Q > P > S > R

(B) P > Q > R > S

(C)Q>P>R>S

(D)P>Q>S>R

ANS
...
GPATINDIA
...
126 The following statements are given:
[P] Conformational isomers are interconvertible by rotation around a single bond while
configurational isomers cannot be interconverted without breaking a bond
...

Choose the correct combination of statements
...
B (MINOR + SEMI MAJOR)
Q
...
Choose that
...
A (MINOR TEST)
Q
...

: Aldehydes can undergo both Cannizaro as well as Aldol condensation while
ketones undergo only Cannizaro reaction
...
B (SEMI MAJOR)
Q
...

(C) These reactions show a large element effect
(D) These reactions are not accompanied by hydrogen exchange
ANS
...
130 Choose the correct statement for writing the sequence of amino acids in a polypeptide?
(A)

Amino terminal is to be written on the left hand side while the carboxyl terminal is to
written on the right hand side
(B) Carboxyl terminal is to be written on the left hand side while the amino terminal is to
written on the right hand side
(C) Any of the amino acid terminals can be written on any sides but it is to be mentioned
specifying the amino terminal and the carboxyl terminal in abbreviations
(D) It varies from author to author how the sequence of amino acids in a polypeptide is to
written

be
be
by
be

ANS
...
131 BETA-Carboline ring system is present in
(A) Emetine

(B) Riboflavine

(C) Deserpidine

(D) d-Tubocurarine

ANS
...
132 Which one of the followings is NOT a bioisosteric pair?
(A) Divalent ether (-0-) and amine (-NH)

(B) Hydroxyl (-OH) and thiol (-SH)

(C) Carboxylate (C02-) and sulfone (S02)

(D) Hydrogen (-H) and fluorine (-F)

ANS
...
133 Of the four stereoisomers of chloramphenicol which one is the biologically active isomer?
(A) L-Erythro

(B) L-Threo (C) D-Erythro

ANS
...
GPATINDIA
...
134 The catalytic triad in acetyl cholinesterase is composed of which of the following amino acid
residues?
(A) Serine, Histidine and Glutamate
(C) Threonine, Histidine and Aspartate

(B) Serine, Arginine and Glutamate
(D) Threonine, Arginine and Glutamate

ANS
...
135

Fajan's method of titrimetric analysis involves detection of the end point on the basis of which
one the followings?
(A) Colour change

(B) Appearance of a precipitate

(C) Neutralization reaction

(D) Adsorption phenomenon

ANS
...
136 Which of the following statements is true?
(A)

Aliphatic protons have chemical shifts > 7 ppm

(B)
(C)
(D)

Spin quantum number of proton is 1
Chemical shift describes electronic environment of a proton
Vicinal coupling constant is always higher than geminal coupling constant

ANS
...
137 'In FT-IR instruments Michaelson interferometer is used in place of grating
...
What do you understand by this statement?
(A)
(B)

The function of the interferometer is to act as a monochromator
The function of the interferometer is to convert high frequency radiations into low ones

(C)
(D)

The function of the interferometer is to convert low frequency radiations into high ones
The function of the interferometer is to convert frequency domain spectra into time
domain spectra

ANS
...
138 Polyamine polystyrene resins belong to which category of ion-exchange resins?
(A)
(B)
(C)
(D)

Strongly Acidic Cation Exchange Resins
Strongly Basic Anion Exchange Resins
Weakly Acidic Cation Exchange Resins
Weakly Basic Anion Exchange Resins

ANS
...
139 Discrepancies in potential measurements involving factors like 'alkaline error' and 'asymmetry
potential' are associated with which of the following electrodes9
(A) Hydrogen electrode

(B) Quinhydrone electrode

(C) Saturated calomel electrode

(D) Glass Electrode

ANS
...
140 Which amongst the following auxochromes produces a shift towards higher energy wave
length?
(A) -CH3

(B) -NHCH3

(C) -CI

(D)

-C=0

ANS
...
141 What is the wave number equivalent of 400 nm wavelength?
(A) 0
...
25 cm-1

(C) 2500 cm-1

(D) 25000 cm-1

ANS
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142 Chloroform is stored in dark colored bottles because it is oxidized in presence of light and air to

a toxic compound
...

(A) CH2C12

(B) COCl2

(C) CO

(D) CC14

ANS
...
143 All of the given compounds show n —> a* transition
...
D (MINOR TEST)

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PHARMACOPHORE SOLUTIONS-JAIPUR
Q
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13C

Choose the correct combination of statements
...
D (MINOR + SEMI MAJOR TEST -50% QUESTION SIMMILAR)
Q
...
D
Q
...
C (MINOR TEST)
Q
...
A
Q
...
500 at 250 nm at a path length of 10
mm
...
002 cm-1 gm-1 litre
Ans
...
002 cm-1 gm-1 dl

(C) 20 cm-1gm-1 litre ( D )

20 cm-1 gm-1 dl

Q
...
D (MINOR TEST)
Q
...

Change in Enthalpy of the reaction has a negative value
Change in Entropy of the reaction has a positive value
Based on the above statements choose the correct answer
...

is non-spontaneous
...

can never be spontaneous
...
A (MINOR TEST)

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PHARMACOPHORE SOLUTIONS-JAIPUR
DEAR STUDENTS
1
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ACCORDING TO GPATINDIA
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THE CUT OFF MARKS
WILL BE AROUND 30-40% MARKS
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SO DON’T WORRY STUDENTS
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MED
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CEUTICS,
BIOCHEMISTRY, QUE
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HOWEVER RECENTLY ADDED ORGANIC CHEMISTRY HAVE GOOD NO
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4
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DONOT WAIT FOR GPAT-11 RESULT
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YOU CAN JOIN OUR PRE-NIPER TEST SERIES-2011-TOTAL 10 MOCK TEST-200 QUESTION
IN EACH PAPER
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GPAT-2012 ON LINE TEST SERIES
STARTING FROM 15th JULY 2011
Here we provide latest information regarding GPAT-2012 Test Series
...

According to New Syllabus of GPAT-11 we have change syllabus of our tests;


Total 26 (Twenty Six:- 20 –Minor, 2-Semi Major & 4 – Major)
Test will be conducted till GPAT-2011



NOTE:-YOU CAN JOIN THE TEST SERIES TILL (Till April 2012 last
week) GPAT-2012, ANY TIME WHEN YOU COME TO KNOW ABOUT IT,
THROUGH ANY SOURCE
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, For Each Semi Major & Major- 180
min (3 Hr)
Total Question In Each Minor Test- 60
Total Question In Each Semi Major Test-100
Total Question In Each Major Test-150
Test Place: Any Cyber Cafe, Your College/Institute Net, Internet Facility
is Necessary
Day & Timing of Test: Any Time , Any Day – Till GPAT-2012
Negative Marking System: Same as GPAT-2011 (1/3 marks deduction on
every wrong answer)
You can avail these papers every time, everywhere, there is no schedule
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Result: Result of your test will be display after completion of your every
test (Within 1 sec
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Fill the Registration form For GPAT-2011 Test Series at – www
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or
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Our account details are as
follows:
Bank Name: Punjab National Bank at Jaipur
Branch IFSC No: PUNB0395300
Name of the Account holder: Pharmacophore Solutions
Account Type: Current
Account Number: 3953002100013904
or

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Title: Practice papers
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