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Title: Eukaryotic Transcription
Description: Essay on the mechanism of transcription in eukaryotic organisms.
Description: Essay on the mechanism of transcription in eukaryotic organisms.
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EUKARYOTIC TRANSCRIPTION
Eukaryotic transcription occurs inside the nucleus
...
Elongation then follows where a
protein dimer unwinds the DNA ahead of RNA Pol II while the latter synthesizes mRNA in a 5’ to
3’ direction by adding a complementary nucleotide that enters through the NTPs channel to
each nucleotide in the template strand
...
The
mRNA will then be nearly identical to the non-template, or coding, strand; however, mRNA will
have the base uracil in place of thymine
...
The
remainder of the transcript is then digested by a 5′-exonuclease while it is still being transcribed
...
Finally, the mRNA undergoes processing in
which a cap is added to its 5’ end by a phosphate linkage, and a string of A nucleotides, called
the poly (A) tail, is added to its 3′ end by the poly (A) polymerase, for protection from
degradation while it is processed and exported out of the nucleus
...
This
process results to a mature mRNA that is ready for translation
Title: Eukaryotic Transcription
Description: Essay on the mechanism of transcription in eukaryotic organisms.
Description: Essay on the mechanism of transcription in eukaryotic organisms.