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Title: Eukaryotic Translation
Description: Essay on the mechanism of translation in eukaryotic organisms.
Description: Essay on the mechanism of translation in eukaryotic organisms.
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EUKARYOTIC TRANSLATION
Eukaryotic translation occurs in the cytoplasm where ribosomes are located
...
Initiation then begins when the
initiator tRNA, which usually carries methionine, is recruited to the small ribosomal subunit and
forms a complex with eIF2
...
Afterwards, elongation
proceeds as the methionine-carrying tRNA occupies the P (peptidyl) site of the ribosome
...
A peptide bond is then formed
between the amino acids in the P site which is catalyzed by peptidyl transferase
...
The first tRNA is moved to the E (exit) site and is released from the
ribosomal complex to be recharged with free amino acids again
...
Termination follows when a stop codon (UAA, UAG, or UGA) in
mRNA enters the A site, and is recognized by release factors
...
The RF attaches to the last tRNA and
hydrolyzes the ester linkage between tRNA and the last amino acid, releasing the polypeptide
chain
...
Title: Eukaryotic Translation
Description: Essay on the mechanism of translation in eukaryotic organisms.
Description: Essay on the mechanism of translation in eukaryotic organisms.