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UNIVERSITY OF THE PEOPLE
BIOL 1121 Health Biology
Written Assignment 5
Anonymous
5/12/2020
Introduction:
Endocrine signals are signals from distant cells, which are from the endocrine cells located in
the endocrine gland
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The endocrine signal released a hormone called insulin
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Insulin
also helps in the storage of nutrients in the form of glycogen, lipids, and protein and failure to
control the level of nutrients can lead to diabetes
...
d
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Because of the
large distance to cover, the hormones become diluted and present in low concentrations when
acting on their target cells
...
Glucose disposal into muscle is the major component
of insulin action that prevents postprandial hyperglycemia
...
(Hooper, 2019)
Calcium (Ca2+) is essential for numerous physiological functions, which include intracellular
signalling processes, neuronal excitability, muscle contraction and bone formation
...
Ca2+ makes its way
into the endocrine system through TRPV5, Ca2+ bound to calbindin-D28K diffuses to the basolateral
side, where it is extruded into the blood compartment through NCX1 and to a lesser extent PMCA1b
...
In the blood compartment, PTH, 1,25(OH)2D3 and estrogen increase the transcription and
protein expression of the luminal Ca2+ channels, calbindins, and the extrusion systems
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d
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Available online at http://cnx
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85:1
Hooper, C
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Overview of insulin signalling pathways
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abcam
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genome
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kegg
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https://www
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jp/keggbin/search_pathway_text?map=map&keyword=endocrine+signalling&mode=1&viewImage=
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