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Title: A QUICK REVIEW ON BLEEDING TIME & CLOTTING Time
Description: Quick Review for Quiz and Exam
Description: Quick Review for Quiz and Exam
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MLS12
HEMATOLOGY 2 (LABORATORY)
MODULE 2: SUMMARY
Platelet Function
Platelet Count
Platelet Morphology
Qualitative platelet abnormalities
Thrombocytopenia
Bernard-Soulier Syndrome
Bleeding time is dependent on:
1
...
Efficiency of the tissue fluids
3
...
2
...
4
...
Factors Affecting Bleeding Time
Intercapillary pressure
▪ Usually affect Duke Method
Size and depth of the wound
▪ Depends on the age
...
4mm-3mm
▪ For infants: 1
...
FRANCISCO | Page 1 of 2
6
...
Bernard-Soulier Syndrome
▪ Defect GP1b/V/IX complex that affects platelet production and
structure leading to thrombocytopenia
Glanzmann’s Thrombasthenia
▪ Defect in GP IIb/IIIa complex which is essential in binding with the
fibrinogen to initiate a clot formation or platelet aggregation
...
Diagnose and assess bleeding problems
2
...
Rough measurement of all
intrinsic clotting factors in
the absence of tissue
factors
Venipuncture:
70% alcohol
Cotton/plaster
5cc syringe
Tourniquet
LWCT:
Stopwatch
Wipe off the first drop of
blood
...
Fill capillary tube
...
NV: 3-7 minutes
1
...
3
...
Failure to wipe
off first drop of
blood
...
Underfilled
capillary tube
...
Failure to keep
track of the time
...
Wipes of the first drop of
blood
...
Obtain 3 drops of blood
consecutively in a clean
dry glass slide not
touching the skin
...
Stop timer once fibrin
strand formed on the first
drop
...
Failure to wipe off
first drop of blood
...
2
...
Must be ¾
full
...
Failure to keep
track of the time
...
Drying of the blood
sample on the slide
...
Start timer once blood
enters the needle hub of
the syringe
...
Discard remaining 1mL
...
Check for clot formation
starting at tube 1 every
after 5 minutes
...
NV: 5-15 minutes
1
...
3
...
5
...
Shortens
coagulation time
...
Shortens
coagulation time
...
The smaller the more
rapid coagulation
time
...
Must be
37’ C
...
Admixture of blood
and tissue fluids
Title: A QUICK REVIEW ON BLEEDING TIME & CLOTTING Time
Description: Quick Review for Quiz and Exam
Description: Quick Review for Quiz and Exam