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Title: Student Exploration: Hardy-Weinberg Equilibrium
Description: Prior Knowledge Questions (Do these BEFORE using the Gizmo.) 1. A bird’s feather color is controlled by two alleles, D (dark feathers) and d (lighter feathers). Suppose two Dd birds mate. What percentages of DD, Dd, and dd offspring would you predict? Use the Punnett square at right to help determine your

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Name:

Katie Hebert

Student Exploration: Hardy-Weinberg Equilibrium
Directions: Follow the instructions to go through the simulation
...

Vocabulary: allele, genotype, Hardy-Weinberg equation, Hardy-Weinberg principle, heterozygous,
homozygous, incompletely dominant, Punnett square
Prior Knowledge Questions (Do these BEFORE using the Gizmo
...

co
m

1
...
Suppose
two Dd birds mate
...

DD 25%

Dd 50%

d=

Dd

dd

dd 25%

2
...

1:1 ratio of heterozygous (Dd) to homozygous (DD and dd)
...
To determine if one of these factors is affecting a
population, it is useful to know what a population looks like when none of these
factors is present
...
These laws can be explored in the Hardy-Weinberg Equilibrium Gizmo
...
The parrots you see represent a population of 500 parrots
...
In the Gizmo,
select the TABLE tab
...

250

Dd 100

dd 150

sh

DD

2
...
Click Begin, and then click Breed
...

The birds reproduced and layed eggs
...
Click Hatch, and look on the TABLE tab
...

DD 181

Dd 239

dd 80

This study source was downloaded by 100000836193432 from CourseHero
...
coursehero
...

● Check that DD is 50% and dd is 30%
...
Predict: Describe how you expect the proportions of D and d alleles to change over time
...

2
...
After clicking Hatch, fill in the allele and genotype
percentages for generation 1
...

Generation
1

2

3

4

5

60

59
...
7

58
...
5

57
...
1

42
...
8

43
...
3

% of DD genotype

50

36
...
0

32
...
8

32
...
4

49
...
0

49
...
8

% of dd genotype

30

16
...
6

15
...
8

17
...

co
m

Initial
values

3
...


There was a decrease in % D alleles and an increase in % d alleles
...
There was a significant increase in % of Dd genotype
...

4
...
Describe what this graph shows
...
Both colors stay relatively constant
...
Interpret: Select the GENOTYPE GRAPH tab
...


Th

It shows the genotype percentage, giving all 3 possible genotypes DD, Dd, and dd
...
Gather data: On the DESCRIPTION tab, click Reset
...
Fill in the initial
values in the table below, and then run the Gizmo for five generations
...

Generation

Initial
values

1

2

3

4

5

% D alleles

70

70
...
9

72
...
5

71
...
4

29
...
7

28
...
5

This study source was downloaded by 100000836193432 from CourseHero
...
coursehero
...
4

50
...
8

50
...
6

% of Dd genotype

40

38
...
8

43
...
4

39
...
2

8
...
2

7
...
6

7
...

I noticed that the 2nd graph was more constant than the 1st graph
...
Draw conclusions: The Hardy-Weinberg principle states that the proportions of alleles and genotypes in a
population will remain stable as long as the following criteria are satisfied:
Mating is random
...

No natural or artificial selection is occurring
...

The population is relatively large
...

co
m







Describe how well the Hardy-Weinberg principle describes this population of parrots
...

9
...


No because a different allele would have to come into play into order for it to evolve
...

● Set DD to 30% and add to 70%
...
Calculate: You can use the laws of probability to predict how many DD, Dd, and dd offspring will result from
this parent population
...
Identify the current percentage of d alleles in the population
...
Calculate the probability of inheriting a D allele from a parent
...
)

0
...


D
...


0
...


sh

Th

A
...


2
...
Explain why this is true
...

This study source was downloaded by 100000836193432 from CourseHero
...
coursehero
...
Calculate:
Fill in the current p and q values
next to the D and d alleles around the Punnett
square at right
...
Write these values
into the individual squares
...
The
probability of inheriting a D allele from each
parent is p, so the probability of DD is p 2
...
3

d =0
...
3

DD

Dd

d =0
...

co
m

4
...
Use the Punnett square above as a guide
...
In terms of p and q, what is the probability of a
DD offspring?

25%

B
...
In terms of p and q, what is the probability of a
Dd offspring?

50%

5
...


Th

P represents the dominant allele and the q represents the recessive allele
...
Predict: Check that DD is still set to 30% and dd is still set to 70%
...
3 and q = 0
...
Test: Click Begin, Breed, and Hatch
...
com on 11-15-2021 06:49:48 GMT -06:00

https://www
...
com/file/111538976/4-Hardy-Weinberg-Equilibrium-Gizmo-WSpdf/

How close are these to the predicted values? Not close at all
...
Apply: For a dominant/recessive gene, it is often difficult to determine the percentages of dominant and
recessive alleles in a population because individuals that express the dominant trait may be either
homozygous (DD) or heterozygous (Dd)
...

A
...

According to the Hardy-Weinberg equation, calculate the value of q 2
...
84

B
...
Calculate the value of q
...
Recall that p + q is equal to 1
...


43

D
...

co
m

DD

70%

36%

9
...

Set DD to the value given in part D above and add it to 16%
...
Do
the genotype percentages remain relatively constant? Explain
...


Activity C:

Get the Gizmo ready:

A useful
Hardy-Weinberg
ratio

● Click Reset
...

● Turn on Show Hardy-Weinberg quantities
...
Manipulate: The Hardy-Weinberg equation is p 2 + 2pq + q 2 = 1, where p = probability of D, q = probability
of d, p2 = probability of DD, 2pq = probability of Dd, and q2 = probability of dd
...
Look under Show Hardy-Weinberg quantities
...

Rewrite each of these in terms of the variables p and q
...
The third line of the table is the ratio (Dd•Dd) /
(DD•dd)
...
Show your work
...
com on 11-15-2021 06:49:48 GMT -06:00

https://www
...
com/file/111538976/4-Hardy-Weinberg-Equilibrium-Gizmo-WSpdf/

p^2 q^2

4:1

C
...
(Note: In most
populations, the ratio will range from about 2 to 8
...
Experiment: With Dd set to 0%, the initial value of Dd•Dd / DD•dd is 0
...

Record the percentage of DD, Dd, dd, and Dd•Dd / DD•dd for 5 generations in the table below
...
4

25

22
...
4

% Dd genotype

0

51
...
4

55
...
4

45
...

co
m

Initial
values

% dd genotype

50

24
...
6

22

26
...
403

4
...
273

3
...
841

3
...

4
...
If the value of Dd•Dd / DD•dd differs significantly
from 4 (for example, below 2 or above 8), it is a sign that the population is not in equilibrium and selection
may be taking place
...
com on 11-15-2021 06:49:48 GMT -06:00

https://www
...
com/file/111538976/4-Hardy-Weinberg-Equilibrium-Gizmo-WSpdf/
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Title: Student Exploration: Hardy-Weinberg Equilibrium
Description: Prior Knowledge Questions (Do these BEFORE using the Gizmo.) 1. A bird’s feather color is controlled by two alleles, D (dark feathers) and d (lighter feathers). Suppose two Dd birds mate. What percentages of DD, Dd, and dd offspring would you predict? Use the Punnett square at right to help determine your