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Title: Blueprint Series Lodish Molecular Cell Biology Complete Solution Chapter 10
Description: Molecular Cell Biology by Harvey Lodish is a renowned book taught all over the world and it is liked by around 90% of students. This is the first-ever complete chapter-by-chapter solution of the book. I hope it will be of immense usefulness for those who want to have a very high-end result in their exams because sometimes it is not possible to go through the whole book.
Description: Molecular Cell Biology by Harvey Lodish is a renowned book taught all over the world and it is liked by around 90% of students. This is the first-ever complete chapter-by-chapter solution of the book. I hope it will be of immense usefulness for those who want to have a very high-end result in their exams because sometimes it is not possible to go through the whole book.
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Blueprint Series
Complete Solution
Chapter 10
10
POST-TRANSCRIPTIONAL
GENE CONTROL
REVIEW THE CONCEPTS
1
...
2
...
Enzymes involved in mRNA capping, splicing, and polyadenylation are
recruited to the phosphorylated CTD, which activates them
...
3
...
Because of these sequences, the snRNPs of the spliceosome are recruited to
the proper location on the mRNA
...
While RNA nucleotides have an OH group at both
the 2’ and 3’ carbons, the 3’ carbon of the branch point A is connected to an adjacent
nucleotide
...
4
...
Small nuclear
RNAs (snRNAs) bind to splice sites and participate in splicing reactions
...
Micro RNAs (miRNAs) and short, interfering RNAs (siRNAs) are involved in
gene silencing
...
5
...
In group II intron self-splicing, the introns alone form
a complex secondary structure involving numerous stem loops, whereas spliceosomal splicing utilizes snRNAs interacting with the 5’ and 3’ splice sites of
pre-mRNAs, which form a three-dimensional RNA structure functionally analogous to the group II intron
...
In these experiments, domains I and V are deleted,
and this yields a group II intron incapable of self-splicing
...
This shows that portions of group II introns can
be trans-acting like snRNAs
...
In muscle cells, the internal polyadenylation site could be spliced out of the
mature RNA when the fifth intron is removed
...
In other cells, the fifth intron may not
be spliced out
...
In this scenario, a muscle-specific splicing factor could facilitate
removal of the fifth intron
...
RNA editing is a type of pre-mRNA processing, altering the sequence of the premRNA that results in a mature mRNA differing from the exons encoding it in
genomic DNA
...
A case for RNA editing in humans
involves the serum protein apoB, which forms large lipoprotein complexes that
carry lipids in serum
...
RNA editing occurs in intestinal
cells, where a single base alteration converts a
Title: Blueprint Series Lodish Molecular Cell Biology Complete Solution Chapter 10
Description: Molecular Cell Biology by Harvey Lodish is a renowned book taught all over the world and it is liked by around 90% of students. This is the first-ever complete chapter-by-chapter solution of the book. I hope it will be of immense usefulness for those who want to have a very high-end result in their exams because sometimes it is not possible to go through the whole book.
Description: Molecular Cell Biology by Harvey Lodish is a renowned book taught all over the world and it is liked by around 90% of students. This is the first-ever complete chapter-by-chapter solution of the book. I hope it will be of immense usefulness for those who want to have a very high-end result in their exams because sometimes it is not possible to go through the whole book.