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Title: Types of Bioreactor
Description: Complete detail about bioreactor, its application in industry, advantages and disadvantages of using bioreactor. These notes help students very much.

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Bioreactors
A bioreactor is a vessel in which a chemical
process is carried out which involves
organisms or biochemically active substances
to produce our desire products
...

 Bioreactor can be use in a lab or at
industrial scale
...
Stirred Tank Bioreactor
Mixing method:
Mechanical agitation
Baffles are usually used to reduce
vortexing
...

• High shear forces may damage
cells
...




Size limitations by Motor size , shaft length & weight
...
Bubble column reactor
Mixing method: Gas sparging
Gas-liquid mass transfer coefficients depend
largely on bubble diameter and gas hold-up
...

• High pressure air required
...


3
...


Liquid circulates in an airlift reactor
as a result of density difference
between riser and downcomer
...




Very low cost

Disadvantages:


greater air and high pressure needed
...


4
...


• Working:
• Filled with packed material
...

• Reaction take place on the surface of
catalyst
...


Advantages & Disadvantages
Advantages:


Higher conversion per unit mass
Catalyst then other catalytic reactors
...




Continuous operation



Effective at high temperature & pressure
...

• Difficult to clean
...

• Undesirable side reactions
...
Trickle bed Bioreactor
• A trickle-bed reactor (TBR)
• It is a chemical reactor
...


• It use in the downward movement
of a liquid and gas over a packed
bed of catalyst particles
...

• Immobilized enzyme reaction
...

Booth liquid and solid phase can use in it
...

More efficient
Sterilized reaction
...


Disadvantages:
• The hydrodynamics in the reactor are extremely complex
...

• unsteady state operation
...
Fluidized bed reactor
• FBR is a type of reactor
device that can be used to
carry out a variety of
chemical reactions
...
This
process, known as
fluidization
...


Advantages & Disadvantages
Advantages:


Uniform particle mixing
...




Ability to operate reactor in continuous state
...




Pumping requirement and pressure drop
...




Erosion of internal components
...


7
...

Working:
• Process of photosynthesis
use to generate biomass from
light and carbon dioxide
within the artificial
environment
...

A photo bioreactor allows
• much higher growth rates
• purity levels as in natural
environment
...


• Large surface to volume ratio
...

• Reduction in evaporation of growth
medium
...


Disadvantages:
• Capital cost is very high
...


8
...

• It widely used for
municipal and industrial
wastewater treatment
...
e
...


• Substrate and enzyme can be easily replaced
...


Disadvantages:
• High operating cost
...


9
...

• High pressure gas is used
...

• For semi-liquid material
...

• Also used for water

treatment
...




Good mixing facilitates
better growth
and impart less
hydrodynamics stress
Title: Types of Bioreactor
Description: Complete detail about bioreactor, its application in industry, advantages and disadvantages of using bioreactor. These notes help students very much.