Notesale: Turn your study into money

Document Preview

Extracts from the notes are below, to see the PDF you'll receive please use the links above

---

LIPOPROTEIN
• Lipoproteins are molecular complexes that consist of lipids and proteins (conjugated proteins)
...
Lipoproteins deliver the lipid components (cholesterol,
triacylglycerol etc
...


Structure of lipoproteins
 A lipoprotein basically consists of a neutral lipid core (with triacylglycerol and/or cholesteryl ester) surrounded
by a coat shell of phospholipids, apoproteins and cholesterol
...


Classification of lipoproteins
Five major classes of lipoproteins are identified in human plasma, based on
their separation by electrophoresis
1
...
They consist of highest
(99%) quantity of lipid and lowest (1%) concentration of protein
...

2
...

3
...
They transport cholesterol from liver to other tissues
...
High density lipoproteins (HDL) : They are mostly synthesized in liver
...
HDL particles transport cholesterol from peripheral
tissues to liver (reverse cholesterol transport)
...
Free fatty acids—albumin : Free fatty acids in the circulation are in a bound
form to albumin
...
This lipoprotein cannot be separated by electrophoresis
...


Apolipoproteins (apoproteins)
The protein components of lipoproteins are known as apolipoproteins or, simply, apoproteins
...
Act as structural components of lipoproteins
...
Recognize the cell membrane surface receptors
...
Activate enzymes involved in lipoprotein metabolism
...


COMPOSITION OF APOLIPOPROTEIN
LIPIDS OF LIPOPROTEIN

APOLIPOPROTEIN OF LIPOPROTEINS:

FUNCTIONS OF LIPOPROTEINS

DETERMINATION OF SERUM LIPIDS



---