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Title: Aortic Valvular Disease Notes
Description: Pathophysiology, epidemiology, treatment and anatomy of the aortic valve diseases ( aortic stenosis and aortic regurgitation)

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VALVULAR  DISEASE  NOTES  
 
Valvular  disease  is  damage  or  a  defect  to  one  or  more  of  the  heart  valves
...
 Its  function  is  to  prevent  
the  regurgitation  of  blood  from  the  aorta  
back  into  the  left  ventricle
...
   
 
It  is  comprised  of  3  half  moon  shaped  cusps  
and  3  commissures
...
   
 
 
AO  STENOSIS:  
The  obstruction  of  blood  flow  across  the  aortic  valve  from  the  left  ventricle
...
   
 
There  is  a  build  up  of  pressure  in  the  LV  so  there  is  compensatory  LVH
...
 The  LV  
needs  more  oxygen  to  overcome  the  high  afterload  but  oxygen  demands  can  not  be  met  –  
leads  to  angina  symptoms    
 
Risk  Factors:  
• Hypertension  
• Diabetes  
• Smoking  
• Hypercholesterolemia    
 
Treatment:  
Balloon  valvuloplasty  –  Balloon  inserted  into  heart  and  inflated  to  try  and  open  the  valve
...
 
 
Valve  replacement  –  bio-­‐prosethetic/  mechanical    
 
TAVI  –  transcathater  aortic  valve  implant,  it  is  as  an  alternative  to  open  heart  surgery  

AO  REGURGITATION:  
 
Diastolic  flow  of  blood  from  aorta  to  LV  due  to  incompetence  of  the  valve  or  valvular  
apparatus
Title: Aortic Valvular Disease Notes
Description: Pathophysiology, epidemiology, treatment and anatomy of the aortic valve diseases ( aortic stenosis and aortic regurgitation)