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Outline and evaluate one or more biological explanation of schizophrenia
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Adoption Studies - 164 adoptees, Finland
biological mothers diagnosed with SZ
6
...
2% control group diagnosed)
genetic liability to SZ “decisively confirmed”

The Dopamine Hypothesis:
• “Neurotransmitters are chemical
messengers that carry, boost or moderate
signals between neutrons"
• SZ results from having an excess of the
neurotransmitter dopamine
• too much dopamine
• too many dopamine receptors
• dopamine receptors too sensitive
• Dopamine found in the limbic system,
disturbance in processes leads to problems
in perception experienced by SZ’s
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E: Hong et al found that a variation of the TPH gene was significantly more
common in Chinese SZ patients than in Chinese controls
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Twin Studies

Adoption Studies

P: There are issues with the research evidence in adoption studies
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Golden Nuggets

Excess Dopamine

E: This means that there may be something different about these mothers that
made them give their children up for adoption
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P: Amphetamines support the dopamine hypothesis
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E: This causes hallucinations and delusions, similar effects to the characteristic
factors of schizophrenia
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Amphetamines



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