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Title: Neuroembryology - overall
Description: Questions related to neuroembryology these are FLASH CARDS These are from final year human physiology but does cover the basics

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Neuroembryology Flash Cards

Name the two types of folding that occurs
during neuroembryological development

What is the germ layer theory?

Cranio-caudal folding
Lateral folding

That the organs of the body develop from
one of the three germ layers

Ectoderm
Name the three germ layers

Mesoderm
Endoderm

Ectoderm – skin and nervous system (the outer
layers of skin)

Each layer gives rise to various tissues and
organs
...
The notochord runs the length of the
embryo
...

This groove runs the length of the embryo (the
ectoderm rolls up and drops down – the mesoderm
covers it)
The formation of the neural tube marks the end of
neuralation
...

Cells in and around the notochord signal the
ectoderm to start folding inwards forming
the neural tube
...


Folding sees formation of two pores, name
these

Anterior (cranial) neuropore
Posterior (caudal) neuropore

Another name for the cranial neuropore?

Rostral (anterior/cranial)

Define primary neurulation

Multisite initiation of the neural tube
closure

At what day is closure of the anterior and
posterior neuropore seen?

Anterior closes on day 25
Posterior closes on day 27

The neural tube will go on to form?

Central nervous system
Retina
Pineal gland
Posterior portion of the pituitary gland

What are neural crest cells?

Specialisation of the neural ectoderm
These are a cluster of cells occurring dorsolaterally on the neural tube

The neural crest cells go on to form…

Cranial and sensory ganglia and nerves
Adrenal medulla
Melanocytes
Brancheal arch cartilages
Heart – the bulbar and conal ridges
Meninges
Cranial mesenchyme and connective
tissue

Name the three layers of the wall of the
neural tube that encases the neural canal

Ependymal layer – ventricular zone
Mantle layer – intermediate zone (grey
matter)
Marginal zone (white matter)

What is the alar plate?

Top portion of grey matter

What is the sulcus limitans?

Groove on either side that runs along the
axis of the canal
Title: Neuroembryology - overall
Description: Questions related to neuroembryology these are FLASH CARDS These are from final year human physiology but does cover the basics