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Poisons to Drugs
About 80% of the world’s population depends entirely on local medicines derived from plant material
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Examples of Poisons Used in Drugs:
 Hemlock (Conium maculatum) is a large biennial herb common throughout Europe
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 The dried unripe fruits of hemlock are formally used as a pain reliever and sedative
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 The plant can prepped for medicinal use by collecting the flowering tops and rapidly drying to collect
the tropane alkaloids contained
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 Foxglove (Digitalis spp
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 Cardiac glycosides inhibit the sodium/potassium pump in the plasma membrane of heart muscle
cells, leading to an increase in cardiac output by increasing the force of contraction in the heart
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 Sweet Clover (melilotus officinalis) is a flowering legume plant
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 Bishop’s Lace/Flower (Ammi majus) contains a psoralen called methoxsalen (xanthotoxin)
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In humans, the handling of fruits can cause
phytophotodermatitis due to an increased sensitivity to UV
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) is an herbaceous, vine like, climbing plant mainly cultivated in Mexico
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 Cotton (gossypium spp
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 Gossypol is used as an anti-hormonal male contraceptive though effects are irreversible
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