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First MBBS 2019 Exam Solution Biochemistry I
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© Exam Hustle
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• BAQ •
1
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i) Silicosis
ii) Postmortem autolysis
iii) Gout
iv) Inclusion cell disease - Defect in protein targeting
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Give chemical composition of Hyaluronic acid & chondroitin sulfate
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3
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Liposomes: They are produced when amphipathic lipids in aqueous medium are
subjected to sonification
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Liposomes are used for administration of a variety of therapeutic substances (drugs,
protein, nucleic acids) in order to target specific organs or tissues
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Give reason-Why excessive ingestion of alcohol results in hypoglycemia?
Metabolism of alcohol (by alcohol dehydrogenase and aldehyde dehydrogenase)
involves the consumption of NAD+ and consequently formation of high NADH
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In alcoholics, hypoglycemia is due to reduced gluconeogenesis
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5
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i) Malonate
ii) Carboxin
iii) Oxalate
iv) Glutarate

6
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The secondary, or preventive, antioxidants work indirectly on limiting lipid oxidation
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Enumerate any four factors affecting nitrogen balance
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Enumerate four enzymes of diagnostic importance for Liver function
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Give fasting & postprandial plasma glucose levels in impaired Tolerance
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Enumerate any two oncosuppressor genes
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Enumerate any four functions of Cholesterol

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