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Title: Edexcel IAL Biology Unit 1 Paper 2022 May/June
Description: Edexcel IAL Biology Unit 1Question Paper 2022 May/June
Description: Edexcel IAL Biology Unit 1Question Paper 2022 May/June
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Please check the examination details below before entering your candidate information
Candidate surname
Centre Number
Other names
Candidate Number
Pearson Edexcel International Advanced Level
Time 1 hour 30 minutes
Paper
reference
Biology
WBI11/01
Advanced Subsidiary
UNIT 1: Molecules, Diet, Transport and Health
You must have:
Scientific calculator, ruler, HB pencil
Total Marks
Instructions
black ink or ball-point pen
...
all questions
...
may be used
...
Information
total mark for this paper is 80
...
Any
diagrams
may NOT be accurately drawn, unless otherwise indicated
...
Advice
each question carefully before you start to answer it
...
• Try
Check
• your answers if you have time at the end
...
Q:1/1/1/
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Turn over
BLANK PAGE
2
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Answer ALL questions
...
Some questions must be answered with a cross in a box
...
1 Water is an important biological molecule
...
Complete the description by writing the most appropriate word on the dotted lines
...
molecule
...
charge
...
in living organisms
...
reactions that break down disaccharides such as
...
(Total for Question 1 = 5 marks)
*P70960A0328*
3
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2 The blood clotting process has to be fast to prevent loss of blood from wounds
...
Explain the advantages of storing thromboplastin inside platelets
...
...
...
...
...
(Total for Question 2 = 6 marks)
*P70960A0528*
5
Turn over
3 Pectinase is an enzyme that breaks down pectin
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(a) What type of molecule is pectinase?
(1)
A
disaccharide
B polysaccharide
C protein
D
triglyceride
(b) Explain why enzymes are described as biological catalysts
...
...
...
...
60
50
Rate of reaction
/ a
...
40
30
20
10
0
20
30
40
50
Temperature / °C
6
*P70960A0628*
(i) Calculate the effect on the rate of reaction of each degree increase in
temperature between 46 °C and 50 °C
...
(1)
Answer
...
u
...
(1)
...
...
The table gives information about some blood vessels in a dog
...
0
40
...
3 × 102
28
...
3
20
...
5 × 102
7
...
2 × 109
8
...
1
3
...
6 × 10−2
large veins
40
0
...
0
vena cava
1
1
...
9
1
...
0
(a) Complete the table
...
(3)
8
*P70960A0828*
(b) Explain why the velocity of blood flow in the large arteries is slower than the
velocity of blood flow in the aorta
...
...
...
...
...
(c) Explain why the total surface area of the capillaries needs to be so high
...
...
...
...
Which diagram represents the wall of a large artery?
(1)
A
Key:
B
endothelial cell layer
elastic fibres
smooth muscle
C
collagen fibres
D
(ii) Draw a diagram, using the style above, to represent the wall of a capillary
...
(a) Hair is made from an insoluble fibrous protein called keratin
...
(2)
1
...
...
...
(ii) Keratin contains a high proportion of the amino acid, cysteine
...
The diagram shows the R group of cysteine
...
(3)
*P70960A01128*
11
Turn over
(b) The effect of two different temperatures on the lengths of the primary structure
and secondary structure of a polypeptide was investigated
...
Structure of
polypeptide
Length of structure / nm
at 25 °C
at 55 °C
primary
505
505
secondary
48
70
(i) Describe the secondary structure of a polypeptide
...
...
...
...
(4)
...
...
...
...
...
...
...
...
(Total for Question 5 = 11 marks)
*P70960A01328*
13
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6 The risk of developing cardiovascular disease (CVD) is dependent on a number
of factors
...
A study was designed to compare perceived risks with actual risks
...
The same group of people were then examined to determine their actual
risks of CVD
...
60
50
Number of
people
40
30
20
10
0
smoking
inactivity
overweight
high blood
cholesterol levels
high blood
pressure
Risk factors
Key:
number of people with a perceived risk
number of people with an actual risk
(i)
Describe two conclusions that can be drawn from this study
...
...
2
...
...
(3)
...
...
...
...
...
(3)
...
...
...
...
...
The Framingham Risk Score uses a point scoring system to estimate the
10‑year risk of developing CVD
...
Table 1
Risk factor
Points per age group
35 to 39
40 to 44
45 to 49
50 to 54
age
−3
0
+3
+6
total cholesterol level / mg dm−3
<160
160 to 199
200 to 239
240 to 279
0
+4
+8
+11
0
+3
+6
+8
0
+3
+6
+8
0
+2
+4
+5
smoker
+9
+7
+7
+4
systolic blood pressure / mm Hg
<120
120 to 129
130 to 139
0
+1
+2
0
+1
+2
0
+1
+2
0
+1
+2
Table 2 shows the 10-year risk for the total points scored, calculated using the
information in Table 1
...
(2)
Answer
...
Use the information in the table to support your answer
...
...
...
...
(2)
...
...
...
(Total for Question 6 = 15 marks)
18
*P70960A01828*
7 The components of a cell membrane determine its properties
...
(a) The table shows one way that the components of phospholipids can be drawn
...
(2)
*P70960A01928*
19
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(ii) One of the bonds present in phospholipids is an ester bond
...
(i) Explain why an increase in temperature increases the fluidity of
the membrane
...
...
...
...
(1)
(2)
...
...
...
(iv) Suggest why a fatty acid with a shorter side chain will increase the fluidity of
a membrane
...
...
*P70960A02128*
21
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(c) Studies have shown that when fish are moved into water at a lower temperature,
the fatty acid content of their membranes changes
...
(2)
...
...
...
(ii) Suggest why these changes are necessary for the survival of the fish
...
...
...
...
(a) Cancer is one of the main causes of death in the world
...
Calculate the ratio of deaths caused by cancer to deaths not caused by cancer
...
(2)
Answer
...
The chart shows the proportion of cancers caused by some types of mutation
...
(1)
1
...
24
*P70960A02428*
(ii) Estimate the percentage of cancers caused by type 3 substitution mutations
...
%
(iii) A type 1 substitution mutation in a gene alters the DNA and mRNA but does
not affect the protein synthesised from the mutated gene
...
(4)
...
...
...
...
...
...
*P70960A02528*
25
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(c) Phenylketonuria (PKU) is a genetic disorder
...
The pedigree diagram shows the phenotypes of individuals in one family affected
by PKU
...
000
B
0
...
250
D
0
...
(6)
...
...
...
...
...
...
...
...
...
(Total for Question 8 = 15 marks)
TOTAL FOR PAPER = 80 MARKS
*P70960A02728*
27
BLANK PAGE
28
*P70960A02828*
Title: Edexcel IAL Biology Unit 1 Paper 2022 May/June
Description: Edexcel IAL Biology Unit 1Question Paper 2022 May/June
Description: Edexcel IAL Biology Unit 1Question Paper 2022 May/June