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Title: Antibiotics part 1
Description: This is short pharmacology notes

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What 's up ninja nerds in this video today we 're going to be talking about antibiotics and
there is so much to talk about it is insane here 's what i really want you guys to do i 'm telling
you it will really benefit you if you do this
...
There is a plethora of
antibiotics within this category of reducing the cross-linking
...
Certain bacteria break down the
beta-lactam ring of the penicillins and render the antibiotic ineffective
...

Some bacteria very nasty bacteria have the ability to produce a very interesting enzyme called
beta lactamase
...
What are the drugs that are going to work to inhibit this beta lactamicase what are
those drugs these are those that we add on
...
The next part will be the bacterial coverage or the antibiotic spectrum of specific
antibiotics
...

Bacteriocidal agents kill bacteria they blow them up the cell membrane integrity they alter the
permeability and increase the risk of blowing the bacteria up so they kill bacteria but this one
it does n't really do anything to kill the bacteria it just reduces the growth or the division of
the bacteria that 's called bacteriostatic
...
Metronidsazole increases the formation of something
called your reactive oxygen species like free radicals that can actually produce damage to the
bacteria
...
They inhibit the dna gyrus they inhibit the actual topoisomerase enzyme
and so it produces a multiple well particularly they inhibit ligating the annealing portion of it
and then they increase the activity of the cutting portion the nucleus portion
...
tobramycin is a is
a good one amy casein is a pretty good one and gentomycin is also a pretty one as well
...

The most common ones that you 'll see on your exam or in the clinical world is going to be
these so misa is what 's called your methicillin sensitive staphylococcus aureus there 's a
couple antibiotics that work relatively well against this without being too broad and so the
ones that i would want you guys to remember is think about first your beta lactams if you
will
...
The other one here will actually just continue on penicillin you
can also consider your amino penicillins
...
These would be the primary ones for strep pneumo if you had out of all of these
which ones would you pick to be the best ones i would say your penicillin your amino
penicils and your third gen cephalosporins would be best ones these ones down here
fluoroquinolones are okay mackerel is a lot of resistance cleaned up and then again on top of
that your tetracycline's not really as well
Title: Antibiotics part 1
Description: This is short pharmacology notes