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Title: MICROBIOLOGY VIRUS RNA and DNA REVIEWERS FOR FINAL EXAM
Description: Capsid =Outer protein coat of a virus Nucleocapsid =capsid and nucleic acid together enveloped virus =outer layer of a virus naked virus =virus without an envelope viral replication process =attachment, penetration, uncoating, synthesis, assembly, and release attachment =this is a stage of viral replication process wherein the virus attaches to a protein or carbohydrate receptor penetration =the virus enters the cell wall uncoating =the capsid is removed to release the viral genome synthesis =this is the production of nucleic acid intracellularly assembly =viral pieces are assembled to create a complete viral particle and the formation of envelope (budding) release =the newly formed viral particle escapes the cell through cell lysis Enveloped DNA viruses =Poxviruses
Description: Capsid =Outer protein coat of a virus Nucleocapsid =capsid and nucleic acid together enveloped virus =outer layer of a virus naked virus =virus without an envelope viral replication process =attachment, penetration, uncoating, synthesis, assembly, and release attachment =this is a stage of viral replication process wherein the virus attaches to a protein or carbohydrate receptor penetration =the virus enters the cell wall uncoating =the capsid is removed to release the viral genome synthesis =this is the production of nucleic acid intracellularly assembly =viral pieces are assembled to create a complete viral particle and the formation of envelope (budding) release =the newly formed viral particle escapes the cell through cell lysis Enveloped DNA viruses =Poxviruses
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MICROBIOLOGY - VIRUS (RNA/DNA)
Capsid =Outer protein coat of a virus
Nucleocapsid =capsid and nucleic acid together
enveloped virus =outer layer of a virus
naked virus =virus without an envelope
viral replication process =attachment, penetration, uncoating, synthesis, assembly, and release
attachment =this is a stage of viral replication process wherein the virus attaches to a protein or
carbohydrate receptor
penetration =the virus enters the cell wall
uncoating =the capsid is removed to release the viral genome
synthesis =this is the production of nucleic acid intracellularly
assembly =viral pieces are assembled to create a complete viral particle and the formation of envelope
(budding)
release =the newly formed viral particle escapes the cell through cell lysis
Enveloped DNA viruses =Poxviruses
Herpesviruses
hepadnaviruses
Non-enveloped viruses =parvoviruses, adenoviruses, papillomaviruses, polyomaviruses
single-stranded linear non-enveloped dna virus =parvoviruses
double-stranded linear non-enveloped dna virus =adenoviruses
double-stranded circular non-enveloped dna virus =papillomaviruses, polyomaviruses
double-stranded linear enveloped dna virus =herpesviruses, poxviruses
double-stranded circular enveloped dna virus =hepadnaviruses
site of latency of adenoviridae =oropharynx
adenoviridae is isolated from what? =from cultures of human adenoids and tonsils
mot of adenoviridae =respiratory droplets
fecal-oral route
direct contact
incubation period of adenoviruses =2-14 days
Diseases of Adenoviridae =pharyngitis
pneumonia
gastroenteritis
site of latency of hepadnaviridae =liver
incubation period of hepadnaviridae =1-3 months or longer
mot of hepadnaviridae =exchange of body secretion
recipient of blood products
percutaneous injection
perinatal
diseases of hepadnaviridae =hepatitis b
liver cancer
6 Hepatitis B Markers =HBsAg, HBeAg, HBcAg, Anti-HBs, Anti-HBe, Anti-HBc
HBsAg =most reliable marker to detect HBV infection
HBeAg =indicates high infectivity or active viral replication
HBcAg =it cannot be detected in the blood, located in the hepatocytes
Anti-HBs =previously vaccinated and has developed immunity
Anti-HBe =indicates convalescence
Anti-HBc =indicates previous or ongoing infection
8 Human Herpes Group Viruses =Herpes Simplex Virus 1&2, Varicella-Zoster Virus, Epstein-Barr Virus,
Cytomegalovirus, Human Herpes Virus 6&7, Human Herpes Virus 8
Herpes Simplex Virus 1&2 =diseases affecting the central nervous system
Varicella-zoster virus =chicken pox and shingles
Epstein-Barr virus =kissing disease
Cytomegalovirus =congenital disease of newborns/ miscarriage
Human Herpes Virus 6&7 =associated roseola; fever and rash on trunk and neck
Human Herpes Virus 8 =Kaposi sarcoma; blood and lymph nodes; at risk are person with AIDS
site of latency of Papillomaviridae =epithelial tissue
mot of papillomaviridae =direct contact
sexual contact for genital warts
diseases of papillomaviridae =skin and genital warts
cervical cancer
HPV (human papilloma vaccine) =to prevent cervical cancer
site of replication of parvovirus =bone marrow for adults
liver cells for fetus
mot of parvoviridae =respiratory secretions
diseases of parvoviridae =erythema infectiosum (fifth disease)
Erythema infectiosum =Fifth disease (Parvovirus B19), aplastic crisis and stillbirth
site of latency of polyomaviridae =kidney
mot of polyomaviridae =respiratory secretions
Diseases of Polyomaviridae =Hemorrhagic cystitis
Hemorrhagic cystitis =inflammation of the urinary bladder
poxviridae =largest and most complex of all viruses
In 1978, Edward Jenner
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Title: MICROBIOLOGY VIRUS RNA and DNA REVIEWERS FOR FINAL EXAM
Description: Capsid =Outer protein coat of a virus Nucleocapsid =capsid and nucleic acid together enveloped virus =outer layer of a virus naked virus =virus without an envelope viral replication process =attachment, penetration, uncoating, synthesis, assembly, and release attachment =this is a stage of viral replication process wherein the virus attaches to a protein or carbohydrate receptor penetration =the virus enters the cell wall uncoating =the capsid is removed to release the viral genome synthesis =this is the production of nucleic acid intracellularly assembly =viral pieces are assembled to create a complete viral particle and the formation of envelope (budding) release =the newly formed viral particle escapes the cell through cell lysis Enveloped DNA viruses =Poxviruses
Description: Capsid =Outer protein coat of a virus Nucleocapsid =capsid and nucleic acid together enveloped virus =outer layer of a virus naked virus =virus without an envelope viral replication process =attachment, penetration, uncoating, synthesis, assembly, and release attachment =this is a stage of viral replication process wherein the virus attaches to a protein or carbohydrate receptor penetration =the virus enters the cell wall uncoating =the capsid is removed to release the viral genome synthesis =this is the production of nucleic acid intracellularly assembly =viral pieces are assembled to create a complete viral particle and the formation of envelope (budding) release =the newly formed viral particle escapes the cell through cell lysis Enveloped DNA viruses =Poxviruses