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Title: Edexcel a level biology question paper 1 june 2024 salters Nuffield + mark scheme
Description: Mark Scheme (Results) Summer 2024 Pearson Edexcel Advanced Level In Biology A Salters – Nuffield (9BN0) Paper 01: The Natural Environment and Species Survive

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Edexcel a level biology
question paper 1 june
2024 salters Nuffield +
mark scheme

Please check the examination details below before entering your candidate information
Candidate surname

Centre Number

Other names

Candidate Number

Pearson Edexcel Level 3 GCE

Wednesday 5 June 2024
Afternoon (Time: 2 hours)

Paper
reference

9BN0/01

Biology A (Salters Nuffield)

 

Advanced

PAPER 1: The Natural Environment and Species

Survival

You must have:
Calculator, HB pencil, ruler

Total Marks

Instructions

Use black ink or ball-point pen
...

Answer all questions
...


the questions in the spaces provided
• Answer
– there may be more space than you need
...


marks for each question are shown in brackets
• The
– use this as a guide as to how much time to spend on each question
...


• In questions marked with an asterisk (*), marks will be awarded for your ability to

structure your answer logically showing how the points that you make are related or
follow on from each other where appropriate
...


Try to answer every question
...

Turn over

P74456A

©2024 Pearson Education Ltd
...



Energy flow through this ecosystem has been studied
...




The gross primary productivity (GPP) for this ecosystem is 87 069 kJ m–2 yr–1
...




(a) (i) Which of the following is the correct value for the net primary productivity
(NPP) in this ecosystem?

(1)

A
7 025 731 kJ m  yr
–2

–1

B
697 036 kJ m–2 yr–1
C
142 264 kJ m–2 yr–1
D
31 874 kJ m–2 yr–1


(ii) The table shows some information on trophic levels in this ecosystem
...
If you change your mind about an
answer, put a line through the box and then mark your new answer with a cross
...
Write your answers in the spaces provided
...

Give your answer to two significant figures
...




(b) Describe the role of mineral ions in the production of plant biomass
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(a) Describe how carbon dioxide is used in photosynthesis
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(b) The effect of increasing carbon dioxide concentration on photosynthesis in soya
bean plants was investigated
...




Carbon dioxide concentration / ppm

Mean dry mass of leaves / g m–2

160

20
...
1

220

20
...
7

280

21
...
4

330

21
...
4

660

26
...
2

990

30
...
2

(i) Which of the following describes the relationship between the increase in
carbon dioxide concentration and the change in dry mass?

(1)

A
exponential
B
negative correlation
C
positive correlation
D
no correlation


(ii) The measurements were repeated at each concentration to calculate the
mean and standard deviation
...


(3)


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(Total for Question 2 = 9 marks)

6

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Explain why an increase in carbon dioxide concentration above 1000 ppm may
not increase the rate of photosynthesis
...



One of the first people to isolate and test a drug was William Withering
...


(1)


...


Procedure



(2)

Type of trial
William Withering

Contemporary drug trial

Use of a placebo

ü

Testing of dose

ü

Tested on healthy volunteers

ü

Double blind trial

ü

*P74456A0728*

7

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(c) Paclitaxel is a drug used in the treatment of cancer
...

Deduce why Paclitaxel prevents cell division in cancer cells
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(Total for Question 3 = 6 marks)

8

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Cancer involves cells dividing repeatedly in an uncontrolled manner
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It is caused by mutations in the gene coding for the cystic fibrosis transmembrane
conductance regulator (CFTR) protein
...




(a) Describe how a mutation can change the primary structure of a protein
...



...



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...



...




(b) (i) The CFTR protein is produced in cells of the lung and is involved in the
transport of chloride ions
...


(2)


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...


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9

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(ii) Describe how the CFTR protein is transported from the ribosome to the
cell membrane
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(c) The most common mutation in the CFTR gene produces a protein that has the
incorrect shape
...


(3)


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(Total for Question 4 = 11 marks)

10

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(3)

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5 Photosynthesis takes place in the chloroplast
...

L

J

N
(Source: © Kazakova Maryia / Shutterstock)



(i) Which part of the chloroplast is labelled L?
A
a plasmid containing chloroplast DNA

(1)

B
the matrix where the Krebs cycle takes place
C
the stroma where the Calvin cycle takes place
D
the thylakoid where the light‑dependent reactions take place


(ii) The part labelled J is

(1)

A
the matrix where the light‑dependent reactions take place
B
the matrix where the light‑independent reactions take place
C
the stroma where the light‑dependent reactions take place
D
the stroma where the light‑independent reactions take place
(iii) Which of the following is stored in the structure labelled N?

(1)

A
chlorophyll
B
glucose
C
lipid
D
starch



*P74456A01128*

11

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...




(ii) The rate of light‑dependent reactions can be measured in
isolated chloroplasts
...

Describe how DCPIP can be used to measure the effect of temperature on the
rate of the light‑dependent reactions in isolated chloroplasts
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(Total for Question 5 = 8 marks)

12

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(1)

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(b) (i) Give the names of two products of the light‑dependent reactions
of photosynthesis
...



This is leading to changes in the germination of plant seeds
...




(a) Describe the structure of starch
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...



...


The percentage germination of these seeds at the mean spring temperature for
these woodlands was compared with an increase of 5 °C
...


(3)


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(ii) Global warming can result in climate change
...


(2)


...



...



...




(c) To conserve plant species, seeds may be stored in seed banks
...


(3)


...



...



...



...



...




(a) (i) A population is a group of individuals
A
of different species living in the same habitat

(1)

B
of one species living in different communities
C
of one species living in different ecosystems
D
of one species living in the same habitat


(ii) In the wild, several species of deer can live in the same area
...


(2)


...



...



...




(b) In one species of deer, a mutation has led to the occurrence of white deer
...


The results of a study of one of these reserves are shown in the table
...
Several species of deer can be found
in the UK
...


The allele for brown coats is dominant and the allele for white coats
is recessive
...

p2 + 2pq + q2 = 1
...



(ii) It may be beneficial for a population to contain a higher percentage of
heterozygote individuals
...
Heterozygotes may have an allele which allows for adaptation if
conditions change
...
Heterozygotes reduce genetic diversity
...
A beneficial allele could be recessive and heterozygotes breeding together
may produce a homozygous recessive offspring
...


Devise a procedure that could be used to measure plant biodiversity in these
two areas
...



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(Total for Question 7 = 11 marks)

18

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An area with a large population of deer was compared with an area from which
deer were excluded
...



One of the genes studied was the gene for the enzyme lactase
...




(a) (i) Which of the following statements about the action of lactase is correct?

(1)

A
lactase changes the products of the reaction
B
lactase increases the activation energy of the reaction
C
lactase is used up in the reaction
D
lactase reduces the activation energy of the reaction


(ii) Describe the role of ribosomes in the synthesis of lactase
...



...



...



...



...


The study recorded changes in the frequency of this mutation over the past
4000 years
...
096

0
...
280

0
...
680

0
...
770

0
...
740

0
...


Calculate the percentage increase in the frequency of this mutation in the UK
in the last 4000 years
...


20

*P74456A02028*

%

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In Europe, a single mutation resulted in the continued production of lactase
enzyme by children and adults
...


Many children and adults in Europe have a mutation that allows continued
production of lactase enzyme
...


(4)


...



...



...



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...


(Total for Question 8 = 10 marks)



*P74456A02128*

21

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In some children, hepatitis C can cause serious liver damage
...




(i) Explain the role of a fever in the immune response
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...


Describe how the activation of T helper cells leads to the production
of antibodies
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...


22

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9 Hepatitis C is a virus that can infect the liver
...


The virus causing hepatitis C has a similar structure to HIV
...

Deduce how the hepatitis C virus is able to enter liver cells
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Infection with hepatitis B can be treated with drugs and a vaccine is available
...



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(Total for Question 9 = 15 marks)

24

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10 Resistance of bacteria to antibiotics is an increasing problem
...




Researchers have developed new antibiotics that are effective against a number of
strains of bacteria
...




(a) Which of the following statements describes a bactericidal antibiotic?

(1)

A
a substance that can only be used on the skin
B
a substance that kills bacteria
C
a substance that prevents reproduction of bacteria
D
a substance that prevents reproduction of viruses


(b) Two new antibiotics have been developed: antibiotic A and antibiotic B
...


Each species of bacteria (P and Q) was grown in cultures containing:


antibiotic A



antibiotic B



ciprofloxacin



no antibiotic

Each culture was sampled at 0, 1, 2, 4, 6 and 24 hours and the number of viable
cells was recorded
...




*P74456A02528*

25

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no antibiotic
antibiotic A
antibiotic B
ciprofloxacin

10
8
Log10 viable
cells per cm3 6
4
2
0
0

5

10

15

20

25

20

25

Time / hours
Bacteria species Q

12
10
8
Log10 viable
cells per cm3 6
4
2
0
0

5

10

15

Time / hours


(i) Calculate the mean rate of decrease in the number of cells in the first
four hours for species P for antibiotic B
...

26

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Key:

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Bacteria species P

12

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(ii) Comment on the effectiveness of antibiotics A and B against both species
of bacteria
...



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...




*P74456A02728*

27

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(Total for Question 10 = 13 marks)
TOTAL FOR PAPER = 100 MARKS

28

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Examiners
must mark the first candidate in exactly the same way as they
mark the last
...
Candidates must be
rewarded for what they have shown they can do rather than
penalised for omissions
...




There is no ceiling on achievement
...




All the marks on the mark scheme are designed to be awarded
...
e
...
Examiners should also be
prepared to award zero marks if the candidate’s response is not
worthy of credit according to the mark scheme
...




When examiners are in doubt regarding the application of the
mark scheme to a candidate’s response, the team leader must
be consulted
...


Question
Number
1(a)(i)

Answer

Mark

The only correct answer is D 31874 kJm-2yr-1
...
065%



increase in (core) body temperature (1)



it is part of the non-specific immune response / increases
efficiency of immune response (1)

ALLOW part of the inflammatory
response



the high temperature in a fever destroys the { pathogen /
virus } (1)

ALLOW high temperature denatures
enzymes of pathogens / prevents
replication of viruses
(2)

Question
Number
9(a)(ii)

Answer

Additional guidance

Mark

A description that makes reference to the following


(activated) T (helper) cells release cytokines (1)



B cells stimulated to produce B effector cells (1)



(B effector) cells differentiate into plasma cells (1)



antibodies are released (by plasma cells) (1)

ALLOW activated B cells
(4)

Question
Number
9(b)

Answer

Additional guidance

Mark

An answer that makes reference to the following:


glycoprotein binds to a complementary receptor on the
liver cell (1)



the viral envelope (of the hepatitis C virus) fuses with the
liver cell membrane (1)



(viral) RNA enters the cell (1)

ALLOW GP120 / CD4

IGNORE capsid

(3)

Question
Number
*9(c)

Answer

Mark

Answers will be credited according to candidate’s deployment of knowledge and understanding of the
material in relation to the qualities and skills outlined in the generic mark scheme
...
Additional content included in the response must be scientific and relevant
...
g
...

Vague statements related to consequences are made with
limited linkage to a range of scientific ideas, processes,
techniques and procedures
...

3-4
Demonstrates adequate knowledge and understanding by
selecting and applying some relevant biological
facts/concepts
...

The discussion shows some linkages and lines of scientific
reasoning with some structure
...
g
...
g
...

Consequences are discussed which are supported
Title: Edexcel a level biology question paper 1 june 2024 salters Nuffield + mark scheme
Description: Mark Scheme (Results) Summer 2024 Pearson Edexcel Advanced Level In Biology A Salters – Nuffield (9BN0) Paper 01: The Natural Environment and Species Survive