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GLYCOLYSIS
Glycolysis is the metabolic pathway that converts
Glucose into Pyruvate and, in most organisms occurs in
the liquid part of cells
...
It produces two molecules of Pyruvate, ATP, NADH
and Water
...
It occurs in both
aerobic and anaerobic organisms
...
It occurs in both prokaryotic and eukaryotic
cells
...
Glycolysis consists of 10 steps, in which Glucose is
partially oxidized to Pyruvic acid
...
1
...
2
...
The 10 steps of Glycolysis are ---
Step – 1:
(a) A phosphate group is added to glucose in the
cell cytoplasm, by the action of enzyme
Hexokinase
...
Step – 2:
Glucose – 6 – phosphate is isomerised into Fructose
– 6 – phosphate by the enzyme Phosphoglucoisomerase
...
Step – 4:
The enzyme Aldolase converts Fructose – 1,6 –
bisphosphate and Dihydroxyacetone phosphate, which
are isomers of each other
...
Step – 6:
This steps undergoes two reactions --(a) The Glyceraldehyde – 3 – phosphate
dehydrogenase transfers one hydrogen molecule
from Glyceraldehyde phosphate to NAD to form
NADH
...
Step – 7:
Phosphate
is
transferred
from
1,3
–
bisphosphoglycerate to ADP to form ATP with the help
of Phosphoglycerokinase
...
Step – 8:
The phosphate of both the Phosphoglycerate
molecules is relocated from the third to the second
carbon to yield two molecules of 2 – Phosphoglycerate
by the enzyme Phosphoglyceromitase
...
Step – 10:
A phosphate from Phosphoenolpyruvate is
transferred to ADP to form Pyruvate and ATP by the
action of Pyruvate kinase
...