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Title: Major Mycobacteria (Summary Table)
Description: These tables cover the major mycobacteria and summarize the major points for each species. It makes learning the information much simpler as you can easily compare and contrast the different bacteria. I made this tables for my microbiology course in my first year of medical school. Any student who is currently taking a microbiology course will be able to understand and benefit from these tables.
Description: These tables cover the major mycobacteria and summarize the major points for each species. It makes learning the information much simpler as you can easily compare and contrast the different bacteria. I made this tables for my microbiology course in my first year of medical school. Any student who is currently taking a microbiology course will be able to understand and benefit from these tables.
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General
Pathogenic
mycobacteria
Culture
Transmission
1
...
Bacilli
3
...
Aerobic
Mycobacteria
5
...
Soil and water organisms
7
...
Complex cell wall: less PGN; PGN contains mycolic acid; surface glycoproteins are
M
...
Tuberculous infection: Clinically latent, non-infectious,
Disease
tuberculin positive, 1/3 of earth's population
Characteristics 2
...
Primary infection: TB skin test negative, X-ray negative
(asymptomatic)
2
...
Latent-dormant TB (90% of #1): TB skin test positive, Xray negative or positive
4
...
Late progression (10% of #3): TB skin test positive, X-ray
positive, sputum positive
Immunocompromised host (HIV), certain drugs, certain
Risk Factors
medical conditions
Fever, weight loss, weakness, pneumonia (+/- blood),
scrofula, meningitis (headache), miliary TB (dissemination
to many organs), sterile pyuria, wheezing, excessive
Symptoms sweating, chest pain, difficulty breathing
Diagnosis
Treatment
Prevention
Medical history, physical examination, Mantoux
tuberculin skin test (latent infection), chest radiograph
(apical or posterior segments of upper lobe or superior
segmets of lower lobe; unusual appearance in HIV+;
cannot confirm TB), microscopy (acid fast), culture (used
to confirm diagnosis, takes 2-3 weeks), DNA-based
detection (PCR amplification of IS6110 or 16S rRNA gene)
1
...
Rifampin (RIF)
3
...
Ethambutol (EMB) or Streptomycin (SM)
Start with all four drugs (8 weeks) and then adjust for drug
sensitivity results and continue with 2 drugs for 16 weeks
Reduce number of contagious individuals,
chemoporphylaxis, identify latent infection, BCG vaccine
M
...
Multiplies very slowly
2
...
Symptoms can take 20 years to appear
1
...
Lepromatous leprosy: high infectivity
1
...
Cell mediated
response, low infectivity
2
...
Depressed immunity, high infectivity
Clinical signs alone
Multidrug therapy: dapsone, rifampicin,
clofazimine
Pathogenesis of TB
TB is also caused by M
...
africanum
M
...
avium paratuberculosis causes para-TB (Johne's disease of ruminants)
Classification of Mycobacteria
Class 1: M
...
tuberculosis
Group 1: Photochromogens (carotenoid production
after light exposure)
M
...
flavescens
Group 3: Slow Growing Nonpigmented
M
...
chelonae
Title: Major Mycobacteria (Summary Table)
Description: These tables cover the major mycobacteria and summarize the major points for each species. It makes learning the information much simpler as you can easily compare and contrast the different bacteria. I made this tables for my microbiology course in my first year of medical school. Any student who is currently taking a microbiology course will be able to understand and benefit from these tables.
Description: These tables cover the major mycobacteria and summarize the major points for each species. It makes learning the information much simpler as you can easily compare and contrast the different bacteria. I made this tables for my microbiology course in my first year of medical school. Any student who is currently taking a microbiology course will be able to understand and benefit from these tables.