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Title: Comparison of DNA and RNA
Description: I have written this notes which covers all the differences between DNA and RNA

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Comparison of DNA and RNA

Key Points

DNA

RNA

Structure

Abbreviations DNA stands for DEOXYRIBONUCLEIC
ACID
Functions
It is responsible for the storage of genetic
code long term

RNA stands for RIBONUCLEIC ACID

DNA is double stranded except some viruses
which have single stranded DNA
DNA have Deoxyribose sugar

It is responsible for transportation of genetic
information from DNA to the cells where proteins
are prepared
RNA is single stranded except few viruses which
have double stranded RNA
RNA contains Ribose sugar

It contains bases i
...
, adenine, guanine,
cytosine and thiamine
Adenine paired with Thiamine

It contains bases i
...
, adenine, guanine, cytosine
and uracil
Adenine paired with Uracil

Chargaff’s
Rule
Genetic
Material
Length

Purine is equal to Pyrimidine so obey rule

Purine is not equal to Pyrimidines so not obey the
rule
RNA is the genetic material in few viruses

Types

RNA has three types
mRNA, rRNA, tRNA
mRNA is present Nucleolus
tRNA and rRNA is present in Cytoplasm

Replication

DNA have only single form in which it is
present in organisms
Present in Nucleus, Nucleolus and the
extrachromosomal DNA in Chloroplast and
Mitochondria
It can replicate itself

Modification

Bases are not modified

Bases are modified

Hydrolysis by
Alkalis
Life time

It cannot be hydrolyzed easily by alkalis
because of stability
It is long lived

It can be easily hydrolyzed because of its instability

Catalytic

Not any natural DNA is catalytic

It is catalytic

Hydrogen
Bonds

Bases pairing through hydrogen bonds occurs
during coil formation

Quantity

Hydrogen bonds are present between the
complementary bases of the opposite strands
such as
AT CG
Its quantity is fixed

Prone

More prone to the UV damage

Less prone to the UV damage

Read

It can be read by polymerase

It can be read by ribosomes

Direction

Read 3’→5’

Formed 5’→3’

Strands
Sugar
Bases
Pairing

Presence

DNA is the genetic material in all living
organisms
DNA contains millions of nucleotides

RNA contains only few thousand nucleotides

It can not replicate but formed by DNA

It is short lived

Its quantity is variable for cell


Title: Comparison of DNA and RNA
Description: I have written this notes which covers all the differences between DNA and RNA