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Title: Muscular Tissue
Description: A comprehensive study guide of a muscular tissue unit.

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Muscular  Tissue  Notes
Three  types  of  muscle:  



Skeletal    








Longest  fibers  
Has  striations    
Voluntary  
Rapid  contractions,  but  tire  easily  

Cardiac  







Attaches  to  bone  

Only  in  the  heart  
Striated  
Involuntary  
Contracts  at  a  steady  rate  over  a  long  period  of  time  

Smooth  



Makes  up  walls  of  hollow  organs  







Stomach,  intestines,  arteries,  urinary  bladder,  respiratory  passages,  
uterus  

Contractions  force  stuff  through  these  passages  (peristalsis)    
No  striations  
Involuntary  
Slow,  sustained  contractions  

Functions  of  Muscle:  






Producing  body  movements  
Maintains  posture  
Storing  and  moving  substances  within  the  body  (urine,  blood,  food,  babies,  etc
...
 The  stimulus  
can  also  be  chemical,  such  as  neurotransmitters,  or  hormonal
...
   




Individual  muscles  are  separated  by  fascia,  which  also  forms  tendons
...
 (muscle  fiber  =  muscle  cell)
...
   



Perimysium  -­‐  surrounds  groups  of  ten  to  one  hundred  fibers
...
 (Dense  irregular  connective  tissue)
...
   

Muscle  Fiber:  




Sarcolemma:  Plasma  membrane  around  muscle  cell  
Sarcoplasm:  Cytoplasm  of  muscle  cell  






filled  with  rod-­‐like  myofibrils  

Sarcoplasmic  Reticulum:  Transport  system  in  muscle  cell  
Myofibrils:  Within  these,  smaller  structures  called  myofilaments  exist  
Myofilaments:  Two  types,  Actin  (thin)  and  Myosin  (thick)    



Myofilaments  form  dark  and  light  bands  (striations)
...
   



The  neurotransmitter  that  crosses  the  gap:  acetylcholine  

• Acetylcholine  is  broken  down  by  cholinesterase    
Sliding  Filament  Theory:  




The  theory  of  how  muscle  contracts  
Occurs  as  the  thin  filaments  slide  past  the  thick  filaments  
What  is  needed:    






Steps:  
1
...

3
...

5
...

7
...

9
...


ATP  
Calcium  
Myosin  &  Actin  
Acetylcholine  
Cholinesterase    

ACh  released,  binding  to  receptors  
Action  potential  reaches  T-­‐tubule  
Sarcoplasmic  reticulum  releases  Calcium  
Active-­‐site  exposure,  cross-­‐bridge  binding  
Contraction  begins  
ACh  removed  by  AChE  
Sarcoplasmic  reticulum  recaptures  Calcium    
Active  sites  covered,  no  cross-­‐bridged  interaction  
Contraction  ends  
Relaxation  occurs,  passive  return  to  resting  length  

Energy  Sources  for  Muscle  Contraction:  



Creatine  Phosphate  







Super  short  bursts  of  energy  (around  15  secs)    
Phosphate  joins  with  ADP  to  make  ATP    
Makes  one  ATP    

Glycolysis  






Anaerobic  

Anaerobic  
30-­‐40  secs  of  energy    
Makes  2  ATPs  &  lactic  acid  

Cellular  Respiration  






Aerobic  
Makes  36  ATPs  
Occurs  in  the  mitochondria  
Slower  process,  but  lasts  longer    

Terms  to  Know:  



Threshold  Stimulus  -­‐  stimulus  strength  increases  until  strong  enough  to  produce  action  
potential,  smallest  amount  needed  to  contract  



All-­‐or-­‐None  Response  -­‐  strength  by  which  muscle  fiber  responds  to  a  stimulus  is  
independent  of  stimulus  strength,  muscle  cannot  partially  contract  










Motor  Unit  -­‐  single  motor  neuron  and  all  muscle  fiber  innervated  by  it  
Recruitment  -­‐  increasing  number  of  muscle  fibers  contracting  
Muscle  Tone  -­‐  constant  tension  by  muscles  for  long  periods  of  time  
Muscular  Hypertrophy  -­‐  increased  in  muscle  size,  myofibrils,  and  nuclei  
Muscular  Atrophy  -­‐  decrease  in  muscle  size,  reversible  except  when  cells  die  
Muscle  Fatigue  -­‐  decreased  capacity  to  work  and  reduced  efficiency  of  muscle  
Muscle  Cramp  -­‐  sudden  and  involuntary  muscle  movement  
Oxygen  Debt  -­‐  insufficient  oxygen  consumption  relative  to  increased  activity  at  onset  of  
exercise    

 
Rigor  Mortis:  





Generally  occurs  around  six  hours  after  death  
Permanent  contraction  of  muscles  
Occurs  when  oxygen  supply  is  used  up  so  ATP  can  no  longer  be  made
...
   

Bacteria  that  causes  tetanus:  Clostridium  tetani    




 

Found  in:  soil,  rust,  and  animal  feces  

Tetanospasmin  causes  muscle  stiffness  and  spasms    


Title: Muscular Tissue
Description: A comprehensive study guide of a muscular tissue unit.