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Title: Muscular Tissue
Description: A comprehensive study guide of a muscular tissue unit.
Description: A comprehensive study guide of a muscular tissue unit.
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Muscular Tissue Notes
Three types of muscle:
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Skeletal
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Longest fibers
Has striations
Voluntary
Rapid contractions, but tire easily
Cardiac
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Attaches to bone
Only in the heart
Striated
Involuntary
Contracts at a steady rate over a long period of time
Smooth
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Makes up walls of hollow organs
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Stomach, intestines, arteries, urinary bladder, respiratory passages,
uterus
Contractions force stuff through these passages (peristalsis)
No striations
Involuntary
Slow, sustained contractions
Functions of Muscle:
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Producing body movements
Maintains posture
Storing and moving substances within the body (urine, blood, food, babies, etc
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The stimulus
can also be chemical, such as neurotransmitters, or hormonal
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Individual muscles are separated by fascia, which also forms tendons
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(muscle fiber = muscle cell)
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Perimysium -‐ surrounds groups of ten to one hundred fibers
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(Dense irregular connective tissue)
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Muscle Fiber:
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Sarcolemma: Plasma membrane around muscle cell
Sarcoplasm: Cytoplasm of muscle cell
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filled with rod-‐like myofibrils
Sarcoplasmic Reticulum: Transport system in muscle cell
Myofibrils: Within these, smaller structures called myofilaments exist
Myofilaments: Two types, Actin (thin) and Myosin (thick)
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Myofilaments form dark and light bands (striations)
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The neurotransmitter that crosses the gap: acetylcholine
• Acetylcholine is broken down by cholinesterase
Sliding Filament Theory:
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The theory of how muscle contracts
Occurs as the thin filaments slide past the thick filaments
What is needed:
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Steps:
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ATP
Calcium
Myosin & Actin
Acetylcholine
Cholinesterase
ACh released, binding to receptors
Action potential reaches T-‐tubule
Sarcoplasmic reticulum releases Calcium
Active-‐site exposure, cross-‐bridge binding
Contraction begins
ACh removed by AChE
Sarcoplasmic reticulum recaptures Calcium
Active sites covered, no cross-‐bridged interaction
Contraction ends
Relaxation occurs, passive return to resting length
Energy Sources for Muscle Contraction:
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Creatine Phosphate
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Super short bursts of energy (around 15 secs)
Phosphate joins with ADP to make ATP
Makes one ATP
Glycolysis
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Anaerobic
Anaerobic
30-‐40 secs of energy
Makes 2 ATPs & lactic acid
Cellular Respiration
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Aerobic
Makes 36 ATPs
Occurs in the mitochondria
Slower process, but lasts longer
Terms to Know:
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Threshold Stimulus -‐ stimulus strength increases until strong enough to produce action
potential, smallest amount needed to contract
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All-‐or-‐None Response -‐ strength by which muscle fiber responds to a stimulus is
independent of stimulus strength, muscle cannot partially contract
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Motor Unit -‐ single motor neuron and all muscle fiber innervated by it
Recruitment -‐ increasing number of muscle fibers contracting
Muscle Tone -‐ constant tension by muscles for long periods of time
Muscular Hypertrophy -‐ increased in muscle size, myofibrils, and nuclei
Muscular Atrophy -‐ decrease in muscle size, reversible except when cells die
Muscle Fatigue -‐ decreased capacity to work and reduced efficiency of muscle
Muscle Cramp -‐ sudden and involuntary muscle movement
Oxygen Debt -‐ insufficient oxygen consumption relative to increased activity at onset of
exercise
Rigor Mortis:
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Generally occurs around six hours after death
Permanent contraction of muscles
Occurs when oxygen supply is used up so ATP can no longer be made
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Bacteria that causes tetanus: Clostridium tetani
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Found in: soil, rust, and animal feces
Tetanospasmin causes muscle stiffness and spasms
Title: Muscular Tissue
Description: A comprehensive study guide of a muscular tissue unit.
Description: A comprehensive study guide of a muscular tissue unit.